Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore
文献类型：期刊论文
| 作者 | Wu, Yueci8; Han, Hai-Hao2,3,4; He, Liu5,6; Li, Li7; Zang, Yi4 ; Li, Jia2,3,4; He, Xiao-Peng5,6; Ding, Yaping7; Cao, Weiguo7; James, Tony D.1,8
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| 刊名 | CHEMICAL COMMUNICATIONS
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| 出版日期 | 2023-04-25 |
| 卷号 | 59期号:34页码:5051-5054 |
| DOI | 10.1039/d2cc06425a |
| 文献子类 | Article |
| 英文摘要 | Peroxynitrite is a reactive oxygen and nitrogen species that participates in various biological reactions. Therefore, it is important to readily detect and track peroxynitrite in biological systems. Here, a novel turn-on probe encapsulated in PEG DSPE-PEG/HN-I was used to fluorescently detect ONOO- rapidly. The encapsulation of HN-I using DSPE-PEG2000 optimizes the sensing performances of the naphthalimide probe and avoids ACQ. Using DSPE-PEG/HN-I to detect changes in the levels of exogenous ONOO- in HepG2 cells and endogenous ONOO- induced by LPS in RAW 267.4 cells was demonstrated. |
| WOS关键词 | NITRIC-OXIDE SYNTHASE ; FLUORESCENT-PROBES ; DELIVERY ; BIOCHEMISTRY ; INFECTION ; DESIGN ; SYSTEM |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000964692200001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/309652]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Li, Jia; He, Xiao-Peng; Ding, Yaping; Cao, Weiguo; James, Tony D. |
| 作者单位 | 1.Henan Normal Univ, Sch Chem & Chem Engn, Xinxiang 453007, Peoples R China 2.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264117, Shandong, Peoples R China; 3.Univ Chinese Acad Sci, 19A Yuquan Rd, Beijing 100049, Peoples R China; 4.Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai 201203, Peoples R China; 5.East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn,Joint Int Res Lab Precis Chem, 130 Meilong Rd, Shanghai 200237, Peoples R China; 6.East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Ctr Materiobiol & Dynam Chem, Sch Chem & Mol Engn,Key Lab Adv Mat, 130 Meilong Rd, Shanghai 200237, Peoples R China; 7.Shanghai Univ, Dept Chem, Shanghai 200444, Peoples R China; 8.Univ Bath, Dept Chem, Bath BA2 7AY, England; |
| 推荐引用方式 GB/T 7714 | Wu, Yueci,Han, Hai-Hao,He, Liu,et al. Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore[J]. CHEMICAL COMMUNICATIONS,2023,59(34):5051-5054. |
| APA | Wu, Yueci.,Han, Hai-Hao.,He, Liu.,Li, Li.,Zang, Yi.,...&James, Tony D..(2023).Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore.CHEMICAL COMMUNICATIONS,59(34),5051-5054. |
| MLA | Wu, Yueci,et al."Selective detection of peroxynitrite using an isatin receptor and a naphthalimide fluorophore".CHEMICAL COMMUNICATIONS 59.34(2023):5051-5054. |
入库方式： OAI收割
来源：上海药物研究所
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