Passive microfluidic devices for cell separation
文献类型：期刊论文
| 作者 | Zhang, Tianlong10; Di Carlo, Dino9; Lim, Chwee Teck8; Zhou, Tianyuan10; Tian, Guizhong10; Tang, Tao8; Shen, Amy Q.7; Li, Weihua6; Li, Ming5; Yang, Yang4
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| 刊名 | BIOTECHNOLOGY ADVANCES
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| 出版日期 | 2024-03-01 |
| 卷号 | 71页码:25 |
| ISSN号 | 0734-9750 |
| 关键词 | Passive microfluidics Cell separation Label-free Hybrid Intelligent |
| DOI | 10.1016/j.biotechadv.2024.108317 |
| 英文摘要 | The separation of specific cell populations is instrumental in gaining insights into cellular processes, elucidating disease mechanisms, and advancing applications in tissue engineering, regenerative medicine, diagnostics, and cell therapies. Microfluidic methods for cell separation have propelled the field forward, benefitting from miniaturization, advanced fabrication technologies, a profound understanding of fluid dynamics governing particle separation mechanisms, and a surge in interdisciplinary investigations focused on diverse applications. Cell separation methodologies can be categorized according to their underlying separation mechanisms. Passive microfluidic separation systems rely on channel structures and fluidic rheology, obviating the necessity for external force fields to facilitate label-free cell separation. These passive approaches offer a compelling combination of cost-effectiveness and scalability when compared to active methods that depend on external fields to manipulate cells. This review delves into the extensive utilization of passive microfluidic techniques for cell separation, encompassing various strategies such as filtration, sedimentation, adhesion-based techniques, pinched flow fractionation (PFF), deterministic lateral displacement (DLD), inertial microfluidics, hydrophoresis, viscoelastic microfluidics, and hybrid microfluidics. Besides, the review provides an in-depth discussion concerning cell types, separation markers, and the commercialization of these technologies. Subsequently, it outlines the current challenges faced in the field and presents a forward-looking perspective on potential future developments. This work hopes to aid in facilitating the dissemination of knowledge in cell separation, guiding future research, and informing practical applications across diverse scientific disciplines. |
| WOS关键词 | PINCHED FLOW FRACTIONATION ; WHITE BLOOD-CELLS ; DETERMINISTIC LATERAL DISPLACEMENT ; CIRCULATING TUMOR-CELLS ; LABEL-FREE ISOLATION ; CONTINUOUS PARTICLE SEPARATION ; MESENCHYMAL STEM-CELLS ; SIZE-BASED SEPARATION ; HIGH-THROUGHPUT ; CANCER-CELLS |
| 资助项目 | JUST Scientific Research Staring Foundation, China[1022932303] ; Australian Research Council (ARC) Discovery Project[DP200102269] ; National Health and Medical Research Council (NHMRC) Emerging Leadership Fellowship, Australia[GNT2017679] ; Amada Foundation ; NSG Foundation ; Iketani Science and Technology Foundation ; Tateisi Science and Technology Foundation ; JSPS Core-to-Core program, Japan[JPJSCCA20190007] |
| WOS研究方向 | Biotechnology & Applied Microbiology |
| 语种 | 英语 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| WOS记录号 | WOS:001169858700001 |
| 资助机构 | JUST Scientific Research Staring Foundation, China ; Australian Research Council (ARC) Discovery Project ; National Health and Medical Research Council (NHMRC) Emerging Leadership Fellowship, Australia ; Amada Foundation ; NSG Foundation ; Iketani Science and Technology Foundation ; Tateisi Science and Technology Foundation ; JSPS Core-to-Core program, Japan |
| 源URL | [http://ir.idsse.ac.cn/handle/183446/10881]  |
| 专题 | 深海工程技术部_深海资源开发研究室 |
| 通讯作者 | Tian, Guizhong; Yalikun, Yaxiaer |
| 作者单位 | 1.Nara Inst Sci & Technol, Div Mat Sci, Nara 6300192, Japan 2.Wuhan Univ, Inst Technol Sci, Wuhan 430072, Peoples R China 3.Univ Tokyo, Dept Chem, Tokyo 1130033, Japan 4.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya 572000, Hainan, Peoples R China 5.Univ New South Wales, Sch Mech & Mfg Engn, Sydney, NSW 2052, Australia 6.Univ Wollongong, Sch Mech Mat Mechatron & Biomed Engn, Wollongong, NSW 2522, Australia 7.Okinawa Inst Sci & Technol Grad Univ, Micro Bio Nanofluid Unit, Onna Son, Okinawa 9040495, Japan 8.Natl Univ Singapore, Dept Biomed Engn, Singapore 117583, Singapore 9.Univ Calif Los Angeles, Dept Bioengn, Los Angeles, CA 90095 USA 10.Jiangsu Univ Sci & Technol, Coll Mech Engn, Zhenjiang 212100, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Tianlong,Di Carlo, Dino,Lim, Chwee Teck,et al. Passive microfluidic devices for cell separation[J]. BIOTECHNOLOGY ADVANCES,2024,71:25. |
| APA | Zhang, Tianlong.,Di Carlo, Dino.,Lim, Chwee Teck.,Zhou, Tianyuan.,Tian, Guizhong.,...&Yalikun, Yaxiaer.(2024).Passive microfluidic devices for cell separation.BIOTECHNOLOGY ADVANCES,71,25. |
| MLA | Zhang, Tianlong,et al."Passive microfluidic devices for cell separation".BIOTECHNOLOGY ADVANCES 71(2024):25. |
入库方式： OAI收割
来源：深海科学与工程研究所
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