Objective To investigate effects of driving fatigue on working memory. Methods The control group included 12 taxi drivers after adequate rest while the fatigue group included 27 taxi drivers who had been driving for 10h. Digit memory span, words span, Digit Subtraction Test, Random Number Generation test were used. Results Compared with the control（6.60 ±0.40,90.67 ±6.65,158.27 ±29. 12,0.30±0.06,24.29 ±10.59,35.90± 10.64）, driving fatigue group were significantly （ P 〈 0.05 ） different in the number of backward number memory span （5.37 ± 0.72）, percentage of number of right reaction of the number of total reaction of Digit Subtraction Test （ 79.95± 8.04）, total number of RNG （ 88.33± 19.48 ）, RNG （ 0.40±0.05 ）, Coupon （ 12.35 ±12.88） ,NSQ（49.72 ± 8.06）. Conclusion Driving fatigue can decline the working memory.

目的探讨连续驾驶10h疲劳后工作记忆的变化。方法采用连续驾驶10h的出租车司机作为驾驶疲劳组,组间对照研究设计,对照组为充分休息的出租车司机。主要测试数字记忆广度、词语记忆广度、连续减法测验、随机数字生成测验。结果驾驶疲劳组在数字倒背(5.37±0.72)个、正确反应数占总反应数的百分比(79.95±8.04)%、随机数字生成总数(88.33±19.48)个、随机性(0.40±0.05)、数字对偏差的频率(12.35±12.88)%、反应变化前发生反应的平均数(49.72±8.06)个等几项测验内容,同对照组[(6.60±0.40)个、(90.67±6.65)%、(158.27±29.12)个、(0.30±0.06)、(24.29±10.59)%、(35.90±10.64)个]相比均差异有显著性(P<0.05)。结论驾驶疲劳后工作记忆下降。

基金项目：国家自然科学基金（30500159）