Chronic Mild Sleep Restriction Does Not Lead to Marked Neuronal Alterations Compared With Maintained Adequate Sleep in Adults
文献类型：期刊论文
| 作者 | Li, Xue-Ying1,2; Yoncheva, Yuliya3; Yan, Chao -Gan1,2,4,5; Castellanos, Francisco Xavier3,6; St-Onge, Marie -Pierre7,8 |
| 刊名 | JOURNAL OF NUTRITION
 |
| 出版日期 | 2024-02-01 |
| 卷号 | 154期号:2页码:446-454 |
| 关键词 | sleep duration food obesity fMRI functional connectivity |
| ISSN号 | 0022-3166 |
| DOI | 10.1016/j.tjnut.2023.12.016 |
| 通讯作者 | St-Onge, Marie -Pierre(ms2554@cumc.columbia.edu) |
| 英文摘要 | Background: Sleep restriction (SR) has been shown to upregulate neuronal reward networks in response to food stimuli, but prior studies were short-term and employed severe SR paradigms. Objective: Our goal was to determine whether mild SR, achieved by delaying bedtimes by 1.5 h, influences neuronal networks responsive to food stimuli compared with maintained adequate sleep (AS) >7 h/night. Methods: A randomized controlled crossover study with 2 6-wk phases, AS (>= 7 h sleep/night) and SR (-1.5 h/night relative to screening), was conducted. Adults with AS duration, measured using wrist actigraphy over a 2-wk screening period, and self-reported good sleep quality were enrolled. Resting-state and food-stimulated functional neuroimaging (fMRI) was performed at the endpoint of each phase. Resting-state fMRI data analyses included a priori region-of-interest seed-based functional connectivity, whole-brain voxel-wise analyses, and network analyses. Food task-fMRI analyses compared brain activity patterns in response to food cues between conditions. Paired-sample t tests tested differences between conditions. Results: Twenty-six participants (16 males; age 29.6 +/- 5.3 y, body mass index 26.9 +/- 4.0 kg/m(2)) contributed complete data. Total sleep time was 7 h 30 +/- 28 min/night during AS compared with 6 h 12 +/- 26 min/night during SR. We employed different statistical approaches to replicate prior studies in the field and to apply more robust approaches that are currently advocated in the field. Using uncorrected P value of <0.01, cluster >= 10-voxel thresholds, we replicated prior findings of increased activation in response to foods in reward networks after SR compared with AS (right insula, right inferior frontal gyrus, and right supramarginal gyrus). These findings did not survive more rigorous analytical approaches (Gaussian Random Field theory correction at 2-tailed voxel P < 0.001, cluster P < 0.05). Conclusions: The results suggest that mild SR leads to increased reward responsivity to foods but with low confidence given the failure to meet significance from rigorous statistical analyses. Further research is necessary to inform the mechanisms underlying the role of sleep on food intake regulation. |
| 收录类别 | SCI |
| WOS关键词 | FUNCTIONAL CONNECTIVITY ; MOTION ARTIFACT ; ENERGY-INTAKE ; HEAD MOTION ; FOOD ; DEPRIVATION ; IMPACT ; REGISTRATION ; STRATEGIES ; FAILURE |
| 资助项目 | Sci-Tech Innovation 2030-Major Project of Brain Science and Brain-inspired Intelligence Technology[UL1TR001873] ; National Key R&D Program of China[2021ZD0200600] ; National Natural Science Foundation of China[2017YFC1309902] ; 13th Five-year Informatization Plan of Chinese Academy of Sciences[82122035] ; 13th Five-year Informatization Plan of Chinese Academy of Sciences[81671774] ; 13th Five-year Informatization Plan of Chinese Academy of Sciences[81630031] ; Key Research Program of the Chinese Academy of Sciences[XXH13505] ; Beijing Nova Program of Science and Technology[ZDBS-SSW-JSC006] ; Sci-entific Foundation of Institute of Psychology, Chinese Academy of Sciences[Z191100001119104] ; [E2CX4425YZ] |
| WOS研究方向 | Nutrition & Dietetics |
| 语种 | 英语 |
| WOS记录号 | WOS:001188495100001 |
| 出版者 | ELSEVIER SCIENCE INC |
| 资助机构 | Sci-Tech Innovation 2030-Major Project of Brain Science and Brain-inspired Intelligence Technology ; National Key R&D Program of China ; National Natural Science Foundation of China ; 13th Five-year Informatization Plan of Chinese Academy of Sciences ; Key Research Program of the Chinese Academy of Sciences ; Beijing Nova Program of Science and Technology ; Sci-entific Foundation of Institute of Psychology, Chinese Academy of Sciences |
| 源URL | [http://ir.psych.ac.cn/handle/311026/47451]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 通讯作者 | St-Onge, Marie -Pierre |
| 作者单位 | 1.CAS Key Lab Behav Sci, Inst Psychol, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 3.NYU, Grossman Sch Med, New York, NY USA 4.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing, Peoples R China 5.Chinese Acad Sci, Int Big Data Ctr Depress Res, Beijing, Peoples R China 6.Nathan S Kline Inst Psychiat Res, Orangeburg, NY USA 7.Columbia Univ, Irving Med Ctr, Div Gen Med, New York, NY 10032 USA 8.Columbia Univ, Ctr Excellence Sleep & Circadian Res, Irving Med Ctr, New York, NY 10032 USA |
| 推荐引用方式 GB/T 7714 | Li, Xue-Ying,Yoncheva, Yuliya,Yan, Chao -Gan,et al. Chronic Mild Sleep Restriction Does Not Lead to Marked Neuronal Alterations Compared With Maintained Adequate Sleep in Adults[J]. JOURNAL OF NUTRITION,2024,154(2):446-454. |
| APA | Li, Xue-Ying,Yoncheva, Yuliya,Yan, Chao -Gan,Castellanos, Francisco Xavier,&St-Onge, Marie -Pierre.(2024).Chronic Mild Sleep Restriction Does Not Lead to Marked Neuronal Alterations Compared With Maintained Adequate Sleep in Adults.JOURNAL OF NUTRITION,154(2),446-454. |
| MLA | Li, Xue-Ying,et al."Chronic Mild Sleep Restriction Does Not Lead to Marked Neuronal Alterations Compared With Maintained Adequate Sleep in Adults".JOURNAL OF NUTRITION 154.2(2024):446-454. |
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来源：心理研究所
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