Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities
文献类型：期刊论文
| 作者 | Ma, Jin-Hong; Hu, Dan; Deng, Lu-Lu; Li, Jiang; Hao, Xiao-Jiang ; Mu, Shu-Zhen
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| 刊名 | MOLECULES
 |
| 出版日期 | 2022 |
| 卷号 | 27期号:7页码:2161 |
| 关键词 | Sabia discolor Dunn pentacyclic triterpenoids isolation and purification alpha-glycosidase inhibitory activities |
| DOI | 10.3390/molecules27072161 |
| 英文摘要 | Four new pentacyclic triterpenoids named Sabiadiscolor A-D (1 and 7-9) together with eleven known ones were isolated by repeated column chromatography. Their structures were identified and characterized by NMR and MS spectral data as 6 oleanane-type pentacyclic triterpenoids (1-6), 7 ursane-type ones (7-13), and 2 lupanane-type ones (14-15). Except for compound 15, all other compounds were isolated from Sabia discolor Dunn for the first time. Their alpha-glycosidase inhibitory activities were evaluated, which showed that compounds 1, 3, 8, 9, 13, and 15 implied remarkable activities with IC50 values ranging from 0.09 to 0.27 mu M, and the preliminary structure-activity relationship was discussed. |
| WOS记录号 | WOS:000781711200001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/74777]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Ma, Jin-Hong,Hu, Dan,Deng, Lu-Lu,et al. Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities[J]. MOLECULES,2022,27(7):2161. |
| APA | Ma, Jin-Hong,Hu, Dan,Deng, Lu-Lu,Li, Jiang,Hao, Xiao-Jiang,&Mu, Shu-Zhen.(2022).Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities.MOLECULES,27(7),2161. |
| MLA | Ma, Jin-Hong,et al."Pentacyclic Triterpenoids from Sabia discolor Dunn and Their alpha-Glycosidase Inhibitory Activities".MOLECULES 27.7(2022):2161. |
入库方式： OAI收割
来源：昆明植物研究所
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