Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues
文献类型：期刊论文
| 作者 | Dai,Jia-Meng; Yan,Bing-Chao; Kong,Ling-Mei; Hu,Kun ; Li,Xing-Ren; Li,Xiao-Nian; Sun,Han-Dong; Li,Yan; Puno,Pema-Tenzin
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| 刊名 | ORGANIC CHEMISTRY FRONTIERS
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| 出版日期 | 2023 |
| 卷号 | 11期号:1页码:37-46 |
| 关键词 | ENT-KAURANE DITERPENOIDS ABIETANE DITERPENOIDS A-D DIMERS OXIDATION CYCLOADDUCTS ACTIVATION LIGANDS IBX |
| DOI | 10.1039/d3qo01679j |
| 英文摘要 | Two types of novel diterpene heterodimers, isoxerophilins A (1, ent-kaurane-sempervirane) and B (2, ent-kaurane-abietane), were isolated from the roots of Isodon xerophilus. Their structures and absolute configurations were determined by spectroscopic data and single crystal X-ray diffraction analysis. A bioinspired semisynthesis of ten isoxerophilin analogues, featuring a tandem oxidative dearomatization/intermolecular Diels-Alder reaction, has been achieved, and the transformation of ferruginol into a sempervirane scaffold was accomplished by the SIBX-mediated tandem reaction. Compound 12 promotes MICA/B expression on SMMC-7721 cells. |
| WOS记录号 | WOS:001103036700001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/74881]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Dai,Jia-Meng,Yan,Bing-Chao,Kong,Ling-Mei,et al. Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues[J]. ORGANIC CHEMISTRY FRONTIERS,2023,11(1):37-46. |
| APA | Dai,Jia-Meng.,Yan,Bing-Chao.,Kong,Ling-Mei.,Hu,Kun.,Li,Xing-Ren.,...&Puno,Pema-Tenzin.(2023).Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues.ORGANIC CHEMISTRY FRONTIERS,11(1),37-46. |
| MLA | Dai,Jia-Meng,et al."Isoxerophilins A and B, two diterpene heterodimers from Isodon xerophilus: structural elucidation and semisynthesis of isoxerophilin analogues".ORGANIC CHEMISTRY FRONTIERS 11.1(2023):37-46. |
入库方式： OAI收割
来源：昆明植物研究所
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