New Lupanes from Alstonia scholaris Reducing Uric Acid Level
文献类型：期刊论文
| 作者 | Hu, Bin-Yuan; Zhao, Yun-Li; Xu, Yuan; Wang, Xiao-Na; Luo, Xiao-Dong
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| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2024 |
| 卷号 | 90期号:1页码:38-46 |
| 关键词 | Alstonia scholaris Apocynaceae reducing UA levels lupanes PENTACYCLIC TRITERPENES INDOLE ALKALOIDS LEAVES |
| DOI | 10.1055/a-2186-3260 |
| 英文摘要 | Twelve lupanes including three new compounds named alstoscholarilups A-C ( 1 - 3 ) were isolated from the leaves of Alstonia scholaris . Their structures were elucidated by spectroscopic analysis and ECD calculation. Structurally, compound 1 with a rare A ring-seco skeleton formed lactone and degraded C-3, while 2 with a 28- nor and 3 with a 29- nor -lupane skeleton supported the phytochemical diversity and novelty of the plant. Pharmacologically, compounds 4, 7 , and 10 reduced the serum uric acid (UA) levels of mice significantly. |
| 学科主题 | Plant Sciences ; Pharmacology & Pharmacy ; Integrative & Complementary Medicine |
| WOS记录号 | WOS:001085556700001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/74884]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Hu, Bin-Yuan,Zhao, Yun-Li,Xu, Yuan,et al. New Lupanes from Alstonia scholaris Reducing Uric Acid Level[J]. PLANTA MEDICA,2024,90(1):38-46. |
| APA | Hu, Bin-Yuan,Zhao, Yun-Li,Xu, Yuan,Wang, Xiao-Na,&Luo, Xiao-Dong.(2024).New Lupanes from Alstonia scholaris Reducing Uric Acid Level.PLANTA MEDICA,90(1),38-46. |
| MLA | Hu, Bin-Yuan,et al."New Lupanes from Alstonia scholaris Reducing Uric Acid Level".PLANTA MEDICA 90.1(2024):38-46. |
入库方式： OAI收割
来源：昆明植物研究所
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