Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity
文献类型：期刊论文
| 作者 | Zhang,Xian; Fan,Yinzhong; Ye,Ke; Pan,Xiaoyan; Ma,Xujun; Ai,Honglian; Shi,Baobao; Liu,Jikai |
| 刊名 | PHARMACEUTICALS
 |
| 出版日期 | 2023 |
| 卷号 | 16期号:2页码:193 |
| 关键词 | endophyte fungus Xylaria curta cytochalasins isolation and structure elucidation cytotoxicity A-D METABOLITES |
| ISSN号 | 1424-8247 |
| DOI | 10.3390/ph16020193 |
| 英文摘要 | Six previously undescribed cytochalasins, Curtachalasins X1-X6 (1-6), together with six known compounds (7-12) were isolated from the endophytic fungus Xylaria curta E10 harbored in the plant Solanum tuberosum. The structures were elucidated by the interpretation of HRESIMS, UV, and NMR data. The absolute configurations of Curtachalasins X1-X6 were determined by comparison of their experimental and calculated electronic circular dichroism (ECD) spectra. In bioassays, Curtachalasin X1 (1) and X5 (5) showed cytotoxic activity against the MCF-7 cell line with IC50 values of 2.03 mu M and 0.85 mu M, respectively. |
| 学科主题 | Pharmacology & Pharmacy |
| WOS记录号 | WOS:000941690100001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75043]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Zhang,Xian,Fan,Yinzhong,Ye,Ke,et al. Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity[J]. PHARMACEUTICALS,2023,16(2):193. |
| APA | Zhang,Xian.,Fan,Yinzhong.,Ye,Ke.,Pan,Xiaoyan.,Ma,Xujun.,...&Liu,Jikai.(2023).Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity.PHARMACEUTICALS,16(2),193. |
| MLA | Zhang,Xian,et al."Six Unprecedented Cytochalasin Derivatives from the Potato Endophytic Fungus Xylaria curta E10 and Their Cytotoxicity".PHARMACEUTICALS 16.2(2023):193. |
入库方式： OAI收割
来源：昆明植物研究所
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