Expeditious Synthesis of Gwanakoside A and the Chloronaphthol Glycoside Congeners
文献类型:期刊论文
作者 | Cheng, Yuting3; Xia, Yan2; Yuan, Ziqi1; Li, Haotian2; Wang, Jing2; Wang, Yingjie2; Yang, Cai-Guang1![]() |
刊名 | ORGANIC LETTERS
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出版日期 | 2024-03-20 |
卷号 | 26期号:12页码:2425-2429 |
ISSN号 | 1523-7060 |
DOI | 10.1021/acs.orglett.4c00573 |
通讯作者 | Wang, Yingjie(wangyj@sioc.ac.cn) ; Yu, Biao(byu@sioc.ac.cn) |
英文摘要 | The synthesis of gwanakoside A, a chlorinated naphthol bis-glycoside, and its analogues was achieved through stepwise chlorination and donor-equivalent controlled regioselective phenol glycosylation with glycosyl N-phenyltrifluoroacetimidates as donors. Gwanakoside A displayed considerable inhibitory effects against various cancer cells and Staphylococcus aureus strains. |
WOS关键词 | ORTHO-ALKYNYLBENZOATES ; O-GLYCOSYLATION ; EFFICIENT GLYCOSYLATION ; NAPHTHOL DERIVATIVES ; PHENOLS ; CHLORINATION ; CATALYSIS ; CHLORIDE ; DONORS ; ACID |
资助项目 | National Natural Science Foundation of China ; Shanghai Municipal Science and Technology Major Project[22031011] ; Shanghai Municipal Science and Technology Major Project[21861162011] ; National Natural Science Foundation of China[ZDBS-LY-SLH030] ; Key Research Program of Frontier Sciences of CAS[2022YFA1304700] ; National Key Research & Development Program of China |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:001189141800001 |
出版者 | AMER CHEMICAL SOC |
源URL | [http://119.78.100.183/handle/2S10ELR8/310336] ![]() |
专题 | 新药研究国家重点实验室 |
通讯作者 | Wang, Yingjie; Yu, Biao |
作者单位 | 1.Univ Chinese Acad Sci, Shanghai Inst Mat Med, Chinese Acad Sci, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Chem Biol, Shanghai 200032, Peoples R China 3.Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China |
推荐引用方式 GB/T 7714 | Cheng, Yuting,Xia, Yan,Yuan, Ziqi,et al. Expeditious Synthesis of Gwanakoside A and the Chloronaphthol Glycoside Congeners[J]. ORGANIC LETTERS,2024,26(12):2425-2429. |
APA | Cheng, Yuting.,Xia, Yan.,Yuan, Ziqi.,Li, Haotian.,Wang, Jing.,...&Yu, Biao.(2024).Expeditious Synthesis of Gwanakoside A and the Chloronaphthol Glycoside Congeners.ORGANIC LETTERS,26(12),2425-2429. |
MLA | Cheng, Yuting,et al."Expeditious Synthesis of Gwanakoside A and the Chloronaphthol Glycoside Congeners".ORGANIC LETTERS 26.12(2024):2425-2429. |
入库方式: OAI收割
来源:上海药物研究所
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