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Improvement of the selectivity of a molecularly imprinted polymer-based potentiometric sensor by using a specific functional monomer

文献类型：期刊论文

作者Wang, Junhao1,2; Liang, Rongning1; Qin, Wei1,3,4
刊名ANALYTICA CHIMICA ACTA
出版日期2024-04-15
卷号1298页码:7
关键词Potentiometric sensor Molecularly imprinted polymer Specific functional monomer Density functional theory Bisphenol A
ISSN号0003-2670
DOI10.1016/j.aca.2024.342412
通讯作者Liang, Rongning(rnliang@yic.ac.cn) ; Qin, Wei(wqin@yic.ac.cn)
英文摘要Potentiometric sensors based on the molecularly imprinted polymers (MIPs) as the receptors have been successfully developed for determination of various organic and biological species. However, these MIP receptors may suffer from problems of low selectivity. Especially, it would be difficult to distinguish the target analyte from its structurally similar interferents. In this work, we propose a novel strategy that using specific functional monomer to fabricate MIP with high selectivity towards the target molecule. The density functional theory calculations are used to investigate the interactions between the template and the functional monomer. The binding energy between the template and functional monomer can be used as the criterion for identifying the optimal monomer. As a proof-of-concept experiment, bisphenol A (BPA) is chosen as the template and the MIP is synthesized by the precipitation polymerization method using the specific allyl-beta-cyclodextrin (allyl-beta-CD) with high affinity towards BPA as the functional monomer. The high-affinity MIP is employed as the receptor for the construction of the potentiometric sensor. The proposed potentiometric sensor based on the MIP using allyl-beta-CD as the functional monomer shows an improved response performance in terms of selectivity and sensitivity compared to the conventional potentiometric sensor based on the MIP with the common monomer (i.e., methacrylic acid). This allyl-beta-CD MIP-based potentiometric sensor shows a detection limit of 0.29 mu M for BPA, which is about one order of magnitude lower than that obtained by the conventional MIP-based potentiometric sensor. We believe that utilizing a functional monomer with specific recognition ability towards target in the fabrication of MIP could provide an appealing way to construct highly selective MIP-based electrochemical and optical sensors.
WOS关键词MEMBRANE ELECTRODES ; RECOGNITION ; CYCLODEXTRIN ; DESIGN
WOS研究方向Chemistry
语种英语
WOS记录号WOS:001209190700001
资助机构National Natural Science Foundation of China ; Key R & D Program of Shandong Province ; Key Deployment Project of Centre for Ocean Mega -Research of Science, Chinese Academy of Sciences ; Taishan Scholar Program of Shandong Province ; Special Supporting Project of Yantai
源URL[http://ir.yic.ac.cn/handle/133337/35343]  
专题中国科学院烟台海岸带研究所
通讯作者Liang, Rongning; Qin, Wei
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res YIC, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Shandong Key Lab Coastal Environm Proc,YICCAS, Yantai 264003, Shandong, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Qingdao 266237, Shandong, Peoples R China
4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Shandong, Peoples R China
推荐引用方式
GB/T 7714		 Wang, Junhao,Liang, Rongning,Qin, Wei. Improvement of the selectivity of a molecularly imprinted polymer-based potentiometric sensor by using a specific functional monomer[J]. ANALYTICA CHIMICA ACTA,2024,1298:7.
APA Wang, Junhao,Liang, Rongning,&Qin, Wei.(2024).Improvement of the selectivity of a molecularly imprinted polymer-based potentiometric sensor by using a specific functional monomer.ANALYTICA CHIMICA ACTA,1298,7.
MLA Wang, Junhao,et al."Improvement of the selectivity of a molecularly imprinted polymer-based potentiometric sensor by using a specific functional monomer".ANALYTICA CHIMICA ACTA 1298(2024):7.

入库方式： OAI收割

来源：烟台海岸带研究所

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