High-Performance Thin-Layer Chromatography Coupled with Single Quadrupole: Application the Identification and Differentiation of Rehmanniae Radix and Its Different Processing Products from Raw Materials to Commercial Products
文献类型：期刊论文
| 作者 | Jin, Xu; Zhang, Jianqing; Shen, Xuanjing; Yao, Shuai; Xu, Meng; Wang, Cuicui; Li, Jiayuan; Yao, Changliang; Guo, De-an
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| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
 |
| 出版日期 | 2024-04-17 |
| 页码 | 11 |
| 关键词 | HPTLC-MS Rehmanniae radix Rehmanniae RadixPraeparata formulas prescriptions |
| ISSN号 | 0021-8561 |
| DOI | 10.1021/acs.jafc.4c01262 |
| 通讯作者 | Guo, De-an(daguo@simm.ac.cn) |
| 英文摘要 | The authentication of ingredients in formulas is crucial yet challenging, particularly for constituents with comparable compositions but vastly divergent efficacy. Rehmanniae Radix and its derivatives are extensively utilized in food supplements, which contain analogous compositions but very distinct effects. Rehmanniae Radix, also a difficult-to-detect herbal ingredient, was chosen as a case to explore a novel HPTLC-QDa MS technique for the identification of herbal ingredients in commercial products. Through systematic condition optimization, including thin layer and mass spectrometry, a stable and reproducible HPTLC-QDa MS method was established, which can simultaneously detect oligosaccharides and iridoids. Rehmannia Radix and its processed products were then analyzed to screen five markers that could distinguish between raw and prepared Rehmannia Radix. An HPTLC-QDa-SIM method was further established for formula detection by using the five markers and validated using homemade prescriptions and negative controls. Finally, this method was applied to detect raw and prepared Rehmannia Radix in 12 commercial functional products and supplements. |
| 资助项目 | Shanghai Institute of Materia Medica, Chinese Academy of Sciences[GUIKEAA23023035] ; Guangxi Science and Technology Major Program[GUIKEAA22096029] ; Guangxi Science and Technology Major Project[2021ZD0017] ; Science and Technology Major Project of Inner Mongolia |
| WOS研究方向 | Agriculture ; Chemistry ; Food Science & Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:001204966500001 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/310638]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Guo, De-an |
| 作者单位 | Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Xu,Zhang, Jianqing,Shen, Xuanjing,et al. High-Performance Thin-Layer Chromatography Coupled with Single Quadrupole: Application the Identification and Differentiation of Rehmanniae Radix and Its Different Processing Products from Raw Materials to Commercial Products[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2024:11. |
| APA | Jin, Xu.,Zhang, Jianqing.,Shen, Xuanjing.,Yao, Shuai.,Xu, Meng.,...&Guo, De-an.(2024).High-Performance Thin-Layer Chromatography Coupled with Single Quadrupole: Application the Identification and Differentiation of Rehmanniae Radix and Its Different Processing Products from Raw Materials to Commercial Products.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,11. |
| MLA | Jin, Xu,et al."High-Performance Thin-Layer Chromatography Coupled with Single Quadrupole: Application the Identification and Differentiation of Rehmanniae Radix and Its Different Processing Products from Raw Materials to Commercial Products".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2024):11. |
入库方式： OAI收割
来源：上海药物研究所
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