Lateralized Functional Connectivity of the Sensorimotor Cortex and its Variations During Complex Visuomotor Tasks
文献类型：期刊论文
| 作者 | Yang, Yang6,7; Li, Junjun6,7 ; Zhao, Kai5; Tam, Fred4; Graham, Simon J.3,4; Xu, Min2; Zhou, Ke1
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| 刊名 | JOURNAL OF NEUROSCIENCE
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| 出版日期 | 2024-01-31 |
| 卷号 | 44期号:5页码:14 |
| 关键词 | functional connectivity lateralization regional activation variations visuomotor |
| ISSN号 | 0270-6474 |
| DOI | 10.1523/JNEUROSCI.0723-23.2023 |
| 通讯作者 | Zhou, Ke(kzhou@bnu.edu.cn) |
| 英文摘要 | Previous studies have shown that the left hemisphere dominates motor function, often observed through homotopic activation measurements. Using a functional connectivity approach, this study investigated the lateralization of the sensorimotor cortex during handwriting and drawing, two complex visuomotor tasks with varying contextual demands. We found that both left- and right-lateralized connectivity in the primary motor cortex (M1), dorsal premotor cortex (PMd), somatosensory cortex, and visual regions were evident in adults (males and females), primarily in an interhemispheric integrative fashion. Critically, these lateralization tendencies remained highly invariant across task contexts, representing a task-invariant neural architecture for encoding fundamental motor programs consistently implemented in different task contexts. Additionally, the PMd exhibited a slight variation in lateralization degree between task contexts, reflecting the ability of the high-order motor system to adapt to varying task demands. However, connectivity-based lateralization of the sensorimotor cortex was not detected in 10-year-old children (males and females), suggesting that the maturation of connectivity-based lateralization requires prolonged development. In summary, this study demonstrates both task-invariant and task-sensitive connectivity lateralization in sensorimotor cortices that support the resilience and adaptability of skilled visuomotor performance. These findings align with the hierarchical organization of the motor system and underscore the significance of the functional connectivity-based approach in studying functional lateralization. |
| 收录类别 | SCI |
| WOS关键词 | IPSILATERAL MOTOR CORTEX ; HUMAN BRAIN ; RESTING-STATE ; HEMISPHERIC-SPECIALIZATION ; FINGER MOVEMENTS ; ARM MOVEMENTS ; PREMOTOR ; FMRI ; ATTENTION ; NETWORKS |
| 资助项目 | National Science and Technology Innovation 2030 Major Program[2021ZD0203803] ; National Natural Science Foundation of China[32271120] ; Scientific and Technological Innovation 2030-the major project of the Brain Science and Brain-Inspired Intelligence Technology[2021ZD0200500] ; Beijing Natural Science Foundation[5222027] ; Beijing Natural Science Foundation[E2CX3625CX] ; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions[2022SHIBS0003] ; Scientific Foundation of Institute of Psychology, Chinese Academy of Sciences[E2CX3625CX] |
| WOS研究方向 | Neurosciences & Neurology |
| 语种 | 英语 |
| WOS记录号 | WOS:001223046800003 |
| 出版者 | SOC NEUROSCIENCE |
| 资助机构 | National Science and Technology Innovation 2030 Major Program ; National Natural Science Foundation of China ; Scientific and Technological Innovation 2030-the major project of the Brain Science and Brain-Inspired Intelligence Technology ; Beijing Natural Science Foundation ; Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions ; Scientific Foundation of Institute of Psychology, Chinese Academy of Sciences |
| 源URL | [http://ir.psych.ac.cn/handle/311026/47794]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 通讯作者 | Zhou, Ke |
| 作者单位 | 1.Beijing Normal Univ, Beijing Key Lab Appl Expt Psychol, Natl Demonstrat Ctr Expt Psychol Educ, Fac Psychol, Beijing 100875, Peoples R China 2.Shenzhen Univ, Ctr Brain Disorders & Cognit Sci, Sch Psychol, Shenzhen 518060, Peoples R China 3.Univ Toronto, Dept Med Biophys, Toronto, ON M5G 1L7, Canada 4.Sunnybrook Res Inst, Phys Sci Platform, Toronto, ON M4N 3M5, Canada 5.Pingjin Hosp, Inst Brain Trauma & Neurol, Characterist Med Ctr Chinese Peoples Armed Police, Tianjin 300300, Peoples R China 6.Univ Chinese Acad Sci, Dept Psychol, Beijing 100049, Peoples R China 7.Chinese Acad Sci, Inst Psychol, Ctr Brain Sci & Learning Difficulties, CAS Key Lab Behav Sci, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Yang,Li, Junjun,Zhao, Kai,et al. Lateralized Functional Connectivity of the Sensorimotor Cortex and its Variations During Complex Visuomotor Tasks[J]. JOURNAL OF NEUROSCIENCE,2024,44(5):14. |
| APA | Yang, Yang.,Li, Junjun.,Zhao, Kai.,Tam, Fred.,Graham, Simon J..,...&Zhou, Ke.(2024).Lateralized Functional Connectivity of the Sensorimotor Cortex and its Variations During Complex Visuomotor Tasks.JOURNAL OF NEUROSCIENCE,44(5),14. |
| MLA | Yang, Yang,et al."Lateralized Functional Connectivity of the Sensorimotor Cortex and its Variations During Complex Visuomotor Tasks".JOURNAL OF NEUROSCIENCE 44.5(2024):14. |
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来源：心理研究所
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