Identification of Growth-Related Gene BAMBI and Analysis of Gene Structure and Function in the Pacific White Shrimp Litopenaeus vannamei
文献类型：期刊论文
| 作者 | Niu, Ruigang2,3 ; Zhang, Xiaojun1,2,3; Yu, Yang1,2,3; Bao, Zhenning2,3; Yang, Junqing2,3; Yuan, Jianbo1,2,3; Li, Fuhua1,2,3
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| 刊名 | ANIMALS
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| 出版日期 | 2024-04-01 |
| 卷号 | 14期号:7页码:24 |
| 关键词 | single nucleotide polymorphism RNA interference RNA-seq lipid metabolism glucose metabolism |
| ISSN号 | 2076-2615 |
| DOI | 10.3390/ani14071074 |
| 通讯作者 | Zhang, Xiaojun(xjzhang@qdio.ac.cn) |
| 英文摘要 | As one of the most important aquaculture species in the world, the improvement of growth traits of the Pacific white shrimp (Litopenaeus vannamei), has always been a primary focus. In this study, we conducted SNP-specific locus analysis and identified a growth-related gene, BAMBI, in L. vannamei. We analyzed the structure and function of LvBAMBI using genomic, transcriptomic, metabolomic, and RNA interference (RNAi) assays. The LvBAMBI possessed highly conserved structural domains and widely expressed in various tissues. Knockdown of LvBAMBI significantly inhibited the gain of body length and weight of the shrimp, underscoring its role as a growth-promoting factor. Specifically, knockdown of LvBAMBI resulted in a significant downregulation of genes involved in lipid metabolism, protein synthesis, catabolism and transport, and immunity. Conversely, genes related to glucose metabolism exhibited significant upregulations. Analysis of differential metabolites (DMs) in metabolomics further revealed that LvBAMBI knockdown may primarily affect shrimp growth by regulating biological processes related to lipid and glucose metabolism. These results suggested that LvBAMBI plays a crucial role in regulating lipid metabolism, glucose metabolism, and protein transport in shrimp. This study provides valuable insights for future research and utilization of BAMBI genes in shrimp and crustaceans. |
| WOS关键词 | DIFFERENTIATION ; BODY |
| 资助项目 | Natural Sciences Foundation of China |
| WOS研究方向 | Agriculture ; Veterinary Sciences ; Zoology |
| 语种 | 英语 |
| WOS记录号 | WOS:001201606600001 |
| 出版者 | MDPI |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/185158]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Zhang, Xiaojun |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Breeding Biotechnol & Sustainable Aquacult, Wuhan 430072, Peoples R China 2.Univ Chinese Acad Sci, Coll Earth Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Niu, Ruigang,Zhang, Xiaojun,Yu, Yang,et al. Identification of Growth-Related Gene BAMBI and Analysis of Gene Structure and Function in the Pacific White Shrimp Litopenaeus vannamei[J]. ANIMALS,2024,14(7):24. |
| APA | Niu, Ruigang.,Zhang, Xiaojun.,Yu, Yang.,Bao, Zhenning.,Yang, Junqing.,...&Li, Fuhua.(2024).Identification of Growth-Related Gene BAMBI and Analysis of Gene Structure and Function in the Pacific White Shrimp Litopenaeus vannamei.ANIMALS,14(7),24. |
| MLA | Niu, Ruigang,et al."Identification of Growth-Related Gene BAMBI and Analysis of Gene Structure and Function in the Pacific White Shrimp Litopenaeus vannamei".ANIMALS 14.7(2024):24. |
入库方式： OAI收割
来源：海洋研究所
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