Real-time analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics
文献类型：期刊论文
| 作者 | Shang Chun feng2,5,7,8; Wang Yu fan2,3,7; Zhao Mei ting1,6,7 ; Fan Qiu xiang1,6; Zhao Shan2,3; Qian Yu2; Xu Sheng jin2,3; Mu Yu2,3; Hao Jie1,3,6; Du Jiu lin2,3,4
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| 刊名 | nature neuroscience
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| 出版日期 | 2024-03-11 |
| 页码 | 1-5 |
| DOI | 10.1038/s41593-024-01595-6 |
| 英文摘要 | Large-scale imaging of neuronal activities is crucial for understanding brain functions. However, it is challenging to analyze large-scale imaging data in real time, preventing closed-loop investigation of neural circuitry. Here we develop a real-time analysis system with a field programmable gate array–graphics processing unit design for an up to 500-megabyte-per-second image stream. Adapted to whole-brain imaging of awake larval zebrafish, the system timely extracts activity from up to 100,000 neurons and enables closed-loop perturbations of neural dynamics. |
| 源URL | [http://ir.ia.ac.cn/handle/173211/57369]  |
| 专题 | 国家专用集成电路设计工程技术研究中心_实感计算 |
| 通讯作者 | Mu Yu; Hao Jie; Du Jiu lin |
| 作者单位 | 1.Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China. 2.Institute of Neuroscience, State Key Laboratory of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China. 3.University of Chinese Academy of Sciences, Beijing 100049, China 4.School of Life Science and Technology, ShanghaiTech University, Shanghai 200031, China. 5.Shenzhen Institute of Neuroscience, Shenzhen 518057, China. 6.Guangdong Institute of Artificial Intelligence and Advanced Computing, Guangzhou 510700, China. 7.These authors contributed equally 8.Guangdong-Hongkong-Macau Institute of CNS Regeneration, Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Jinan University, Guangzhou 510632, China. |
| 推荐引用方式 GB/T 7714 | Shang Chun feng,Wang Yu fan,Zhao Mei ting,et al. Real-time analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics[J]. nature neuroscience,2024:1-5. |
| APA | Shang Chun feng.,Wang Yu fan.,Zhao Mei ting.,Fan Qiu xiang.,Zhao Shan.,...&Du Jiu lin.(2024).Real-time analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics.nature neuroscience,1-5. |
| MLA | Shang Chun feng,et al."Real-time analysis of large-scale neuronal imaging enables closed-loop investigation of neural dynamics".nature neuroscience (2024):1-5. |
入库方式： OAI收割
来源：自动化研究所
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