中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A Double-Hurdle Quantification Model for Freezing of Gait of Parkinson's Patients

文献类型:期刊论文

作者Ningcun Xu2,3; Chen Wang3; Liang Peng3; Xiao-Hu Zhou3; Jingyao Chen2,3; Zhi Cheng2,3; Zeng-Guang Hou1,3,4
刊名IEEE Transactions on Biomedical Engineering
出版日期2024
页码1 - 12
DOI10.1109/TBME.2024.3402677
英文摘要

Freezing of gait (FOG) leads to an increased risk of falls and limited mobility in individuals with Parkinson's disease (PD). However, existing research ignores the fine-grained quantitative assessment of FOG severity. This paper provides a double-hurdle model that uses typical spatiotemporal gait features to quantify the FOG severity in patients with PD. Moreover, a novel multi-output random forest algorithm is used as one hurdle of the double-hurdle model, further enhancing the model's performance. We conduct six experiments on a public PD gait database. Results demonstrate that the designed random forest algorithm in the double-hurdle model-hyperparameter independence framework achieves outstanding performances with the highest correlation coefficient (CC) of 0.972 and the lowest root mean square error (RMSE) of 2.488. Furthermore, we study the effect of drug state on the gait patterns of PD patients with or without FOG. Results show that “OFF” state amplifies the visibility of FOG symptoms in PD patients. Therefore, this study holds significant implications for the management and treatment of PD.

语种英语
源URL[http://ir.ia.ac.cn/handle/173211/57189]  
专题多模态人工智能系统全国重点实验室
通讯作者Liang Peng; Zeng-Guang Hou
作者单位1.CAS Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences
2.the Faculty of Innovation Engineering, Macau University of Science and Technology
3.the State Key Laboratory of Multimodal Artificial Intelligence Systems, Institute of Automation, Chinese Academy of Sciences
4.the School of Artificial Intelligence, University of Chinese Academy of Sciences
推荐引用方式
GB/T 7714
Ningcun Xu,Chen Wang,Liang Peng,et al. A Double-Hurdle Quantification Model for Freezing of Gait of Parkinson's Patients[J]. IEEE Transactions on Biomedical Engineering,2024:1 - 12.
APA Ningcun Xu.,Chen Wang.,Liang Peng.,Xiao-Hu Zhou.,Jingyao Chen.,...&Zeng-Guang Hou.(2024).A Double-Hurdle Quantification Model for Freezing of Gait of Parkinson's Patients.IEEE Transactions on Biomedical Engineering,1 - 12.
MLA Ningcun Xu,et al."A Double-Hurdle Quantification Model for Freezing of Gait of Parkinson's Patients".IEEE Transactions on Biomedical Engineering (2024):1 - 12.

入库方式: OAI收割

来源:自动化研究所

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。