An attention-based hybrid deep learning framework integrating temporal coherence and dynamics for discriminating schizophrenia
文献类型:会议论文
作者 | Min Zhao1,3,4![]() ![]() ![]() ![]() ![]() ![]() |
出版日期 | 2021-04 |
会议日期 | April 13-16, 2021 |
会议地点 | France |
英文摘要 | The heterogeneity of schizophrenia makes it difficult to discover reliable imaging biomarkers, and most existing fMRI-based classification methods fail to combine temporal coherence between brain regions and temporal dynamics of brain activity. Therefore, we proposed a hybrid framework that takes advantage of both fMRI functional interaction and temporal dynamics to classify psychiatric disorders by combining C-RNN, DNN and SVM. An attention module was also introduced into the C-RNN model to improve classification accuracy and interpretability without increasing the computation complexity. An accuracy of 85% was achieved in a large multi-site fMRI dataset with 542 healthy controls and 558 schizophrenia patients, in which striatum, dorsolateral prefrontal cortex and cerebellum were identified as the most group-discriminative brain regions by the attention module. Note that the proposed framework is an end-to-end general module, which not only shows high superiority in combining multiple sources of information, but also can be easily applied to integrate other multimodal data. |
源URL | [http://ir.ia.ac.cn/handle/173211/57409] ![]() |
专题 | 自动化研究所_脑网络组研究中心 |
通讯作者 | Jing Sui |
作者单位 | 1.NLPR, Institute of Automation, Chinese Academy of Sciences, Beijing, China 2.Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS) Center, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA 3.School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China 4.Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, China |
推荐引用方式 GB/T 7714 | Min Zhao,Weizheng Yan,Dongmei Zhi,et al. An attention-based hybrid deep learning framework integrating temporal coherence and dynamics for discriminating schizophrenia[C]. 见:. France. April 13-16, 2021. |
入库方式: OAI收割
来源:自动化研究所
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。