中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
An attention-based hybrid deep learning framework integrating temporal coherence and dynamics for discriminating schizophrenia

文献类型:会议论文

作者Min Zhao1,3,4; Weizheng Yan1,3,4; Dongmei Zhi1,3,4; Rongtao Jiang1,3,4; Yujin Zhang3,4; Tianzi Jiang1,3,4; Vince D Calhoun2; Jing Sui1,3,4
出版日期2021-04
会议日期April 13-16, 2021
会议地点France
英文摘要

The heterogeneity of schizophrenia makes it difficult to discover reliable imaging biomarkers, and most existing fMRI-based classification methods fail to combine temporal coherence between brain regions and temporal dynamics of brain activity. Therefore, we proposed a hybrid framework that takes advantage of both fMRI functional interaction and temporal dynamics to classify psychiatric disorders by combining C-RNN, DNN and SVM. An attention module was also introduced into the C-RNN model to improve classification accuracy and interpretability without increasing the computation complexity. An accuracy of 85% was achieved in a large multi-site fMRI dataset with 542 healthy controls and 558 schizophrenia patients, in which striatum, dorsolateral prefrontal cortex and cerebellum were identified as the most group-discriminative brain regions by the attention module. Note that the proposed framework is an end-to-end general module, which not only shows high superiority in combining multiple sources of information, but also can be easily applied to integrate other multimodal data.

源URL[http://ir.ia.ac.cn/handle/173211/57409]  
专题自动化研究所_脑网络组研究中心
通讯作者Jing Sui
作者单位1.NLPR, Institute of Automation, Chinese Academy of Sciences, Beijing, China
2.Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS) Center, Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA
3.School of Artificial Intelligence, University of Chinese Academy of Sciences, Beijing, China
4.Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing, China
推荐引用方式
GB/T 7714
Min Zhao,Weizheng Yan,Dongmei Zhi,et al. An attention-based hybrid deep learning framework integrating temporal coherence and dynamics for discriminating schizophrenia[C]. 见:. France. April 13-16, 2021.

入库方式: OAI收割

来源:自动化研究所

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