Surface-Enhanced Raman Scattering Active Core-Shell Ag NPs@Carbon Dots with Enzyme-Mimicking Activities for Label-Free Measurement Cholesterol
文献类型:期刊论文
作者 | J. Ju; L. Li; B. Li; S. Regmi; T. Wang; J. Xu; C. Li and S. Tang |
刊名 | Biosensors
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出版日期 | 2023 |
卷号 | 13期号:10 |
ISSN号 | 20796374 |
DOI | 10.3390/bios13100927 |
英文摘要 | Serological-sensitive testing of cholesterol holds significant value in the fields of healthcare and clinical diagnosis. This study reports on the preparation of peroxidase-mimicking nanozymes through the wrapping of N, S-doped carbon dots (DCDs) on the surface of silver nanoparticles (Ag NPs@DCD). The shell–core structure of Ag NPs@DCD displays peroxidase-mimicking capability, with the potential to catalyze inactive Raman probe molecules into the Raman reporters. Furthermore, a "shell-isolated nanoparticles-enhanced Raman spectroscopy" structure exhibited an enhanced Raman signal of reporter molecules. Ag NPs@DCD were utilized to create a label-free SERS sensing system for high-performance detection of cholesterol in serum samples. These results demonstrate the potential of the novel nanozyme-based SERS approach for clinical diagnosis. © 2023 by the authors. |
URL标识 | 查看原文 |
源URL | [http://ir.ciomp.ac.cn/handle/181722/67575] ![]() |
专题 | 中国科学院长春光学精密机械与物理研究所 |
推荐引用方式 GB/T 7714 | J. Ju,L. Li,B. Li,et al. Surface-Enhanced Raman Scattering Active Core-Shell Ag NPs@Carbon Dots with Enzyme-Mimicking Activities for Label-Free Measurement Cholesterol[J]. Biosensors,2023,13(10). |
APA | J. Ju.,L. Li.,B. Li.,S. Regmi.,T. Wang.,...&C. Li and S. Tang.(2023).Surface-Enhanced Raman Scattering Active Core-Shell Ag NPs@Carbon Dots with Enzyme-Mimicking Activities for Label-Free Measurement Cholesterol.Biosensors,13(10). |
MLA | J. Ju,et al."Surface-Enhanced Raman Scattering Active Core-Shell Ag NPs@Carbon Dots with Enzyme-Mimicking Activities for Label-Free Measurement Cholesterol".Biosensors 13.10(2023). |
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