Electron Conductive and Transparent Hydrogels for Recording Brain Neural Signals and Neuromodulation
文献类型：期刊论文
| 作者 | Q. Liang; Z. Shen; X. Sun; D. Yu; K. Liu; S. M. Mugo; W. Chen; D. Wang and Q. Zhang |
| 刊名 | Advanced Materials
 |
| 出版日期 | 2023 |
| 卷号 | 35期号:9 |
| ISSN号 | 09359648 |
| DOI | 10.1002/adma.202211159 |
| 英文摘要 | Recording brain neural signals and optogenetic neuromodulations open frontiers in decoding brain neural information and neurodegenerative disease therapeutics. Conventional implantable probes suffer from modulus mismatch with biological tissues and an irreconcilable tradeoff between transparency and electron conductivity. Herein, a strategy is proposed to address these tradeoffs, which generates conductive and transparent hydrogels with polypyrrole-decorated microgels as cross-linkers. The optical transparency of the electrodes can be attributed to the special structures that allow light waves to bypass the microgel particles and minimize their interaction. Demonstrated by probing the hippocampus of rat brains, the biomimetic electrode shows a prolonged capacity for simultaneous optogenetic neuromodulation and recording of brain neural signals. More importantly, an intriguing brain–machine interaction is realized, which involves signal input to the brain, brain neural signal generation, and controlling limb behaviors. This breakthrough work represents a significant scientific advancement toward decoding brain neural information and developing neurodegenerative disease therapies. © 2023 Wiley-VCH GmbH. |
| URL标识 | 查看原文 |
| 源URL | [http://ir.ciomp.ac.cn/handle/181722/67671]  |
| 专题 | 中国科学院长春光学精密机械与物理研究所 |
| 推荐引用方式 GB/T 7714 | Q. Liang,Z. Shen,X. Sun,et al. Electron Conductive and Transparent Hydrogels for Recording Brain Neural Signals and Neuromodulation[J]. Advanced Materials,2023,35(9). |
| APA | Q. Liang.,Z. Shen.,X. Sun.,D. Yu.,K. Liu.,...&D. Wang and Q. Zhang.(2023).Electron Conductive and Transparent Hydrogels for Recording Brain Neural Signals and Neuromodulation.Advanced Materials,35(9). |
| MLA | Q. Liang,et al."Electron Conductive and Transparent Hydrogels for Recording Brain Neural Signals and Neuromodulation".Advanced Materials 35.9(2023). |
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