Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity of Ganoderma meroterpenoids
文献类型：期刊论文
| 作者 | Peng,Xing-Rong; Unsicker,Sybille B.; Gershenzon,Jonathan; Qiu,Ming-Hua
|
| 刊名 | NATURAL PRODUCT REPORTS
 |
| 出版日期 | 2023 |
| 关键词 | ENANTIOSELECTIVE TOTAL-SYNTHESIS INDUCED INSULIN-RESISTANCE FRUITING BODIES POLYCYCLIC MEROTERPENOIDS INHIBITORY MEROTERPENOIDS GANOMYCIN I |
| ISSN号 | 1460-4752 |
| DOI | 10.1039/d3np00006k |
| 英文摘要 | Meroterpenoids found in fungal species of the genus Ganoderma and known as Ganoderma meroterpenoids (GMs) are substances composed of a 1,2,4-trisubstituted benzene and a polyunsaturated side chain. These substances have attracted the attention of chemists and pharmacologists due to their diverse structures and significant bioactivity. In this review, we present the structures and possible biosynthesis of representative GMs newly found from 2018 to 2022, as well as chemical synthesis and biological activity of some interesting GMs. We propose for the first time a plausible biosynthetic pathway for GMs, which will certainly motivate further research on the biosynthetic pathway in Ganoderma species, as well as on chemical synthesis of GMs as important bioactive compounds for the purpose of drug development. |
| 学科主题 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy ; Chemistry |
| WOS记录号 | WOS:000969184700001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75275]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Peng,Xing-Rong,Unsicker,Sybille B.,Gershenzon,Jonathan,et al. Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity of Ganoderma meroterpenoids[J]. NATURAL PRODUCT REPORTS,2023. |
| APA | Peng,Xing-Rong,Unsicker,Sybille B.,Gershenzon,Jonathan,&Qiu,Ming-Hua.(2023).Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity of Ganoderma meroterpenoids.NATURAL PRODUCT REPORTS. |
| MLA | Peng,Xing-Rong,et al."Structural diversity, hypothetical biosynthesis, chemical synthesis, and biological activity of Ganoderma meroterpenoids".NATURAL PRODUCT REPORTS (2023). |
入库方式： OAI收割
来源：昆明植物研究所
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