O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50
文献类型：期刊论文
| 作者 | He,Xin; Peng,Guoqing; Luo,Jianying ; Huang,Jian-Ping; Yang,Jing; Yan,Yijun; Gu,Yu-Cheng; Wang,Li; Huang,Sheng-Xiong
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2023 |
| 关键词 | ISOMERIZATION AZOXIDES |
| ISSN号 | 1520-6025 |
| DOI | 10.1021/acs.jnatprod.2c00892 |
| 英文摘要 | Six new azoxy-aromatic compounds (o-alkylazoxymy-cins A-F, 1-6) and two new nitrogen-bearing phenylvaleric/ phenylheptanoic acid derivatives (o-alkylphemycins A and B, 7 and 8) were isolated from Streptomyces sp. Py50. Their structures were elucidated based on HRESIMS, NMR, UV spectroscopic analyses, and X-ray crystallographic data. O-Alkylazoxymycins A-F (1-6) are the first natural examples of azoxy compounds with the azoxy bond attached to the ortho-position of the phenylheptanoic acid or phenylvaleric acid moiety. Compounds 1, 5, and 6 were active against Epidermophyton floccosum with MIC50 values ranging from 10.1 to 51.2 mu M. A plausible biosynthetic pathway of 2 and 3 was proposed. |
| 学科主题 | Plant Sciences ; Pharmacology & Pharmacy |
| WOS记录号 | WOS:000918831800001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75294]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | He,Xin,Peng,Guoqing,Luo,Jianying,et al. O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50[J]. JOURNAL OF NATURAL PRODUCTS,2023. |
| APA | He,Xin.,Peng,Guoqing.,Luo,Jianying.,Huang,Jian-Ping.,Yang,Jing.,...&Huang,Sheng-Xiong.(2023).O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50.JOURNAL OF NATURAL PRODUCTS. |
| MLA | He,Xin,et al."O-Alkylazoxymycins A-F, Naturally Occurring Azoxy-Aromatic Compounds from Streptomyces sp. Py50".JOURNAL OF NATURAL PRODUCTS (2023). |
入库方式： OAI收割
来源：昆明植物研究所
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