Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep.
文献类型：期刊论文
| 作者 | Zhao,Li-Hua; Hu,Zhan-Xing; Hao,Xiao-Jiang ; Zhang,Peng; Zhang,Ji; An,Qiao; Wang,Juan; Yi,Ping; Yuan,Chun-Mao; Zhang,Zhong-Kai
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| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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| 出版日期 | 2023 |
| 卷号 | 71期号:10页码:4394-4407 |
| 关键词 | Sophora tonkinensis Gagnep matrine-type alkaloids anti-TSWV LUPIN ALKALOIDS QUINOLIZIDINE ALKALOIDS SEEDS |
| ISSN号 | 1520-5118 |
| DOI | 10.1021/acs.jafc.2c09003 |
| 英文摘要 | As a continuation of our research on the development of pesticide active quinolizidine alkaloids (QAs) from the family Fabaceae, the chemical constituents of the root of Sophora tonkinensis Gagnep. were systematically investigated. Seventeen new matrine-type alkaloids (1-17), including one new naturally occurring compound (17), along with 20 known ones were isolated from the EtOH extract of S. tonkinensis. Notably, compound 5 possessed an unprecedented 6/6/5/4/6/6 hexacyclic system. Their structures were confirmed via comprehensive spectroscopic data analysis (IR, UV, NMR, HRESIMS), ECD calculation, and X-ray crystallography. Biological tests indicated that compounds 1, 4, 10, 12, 13, and 30 displayed significant anti-tomato spotted wilt virus (TSWV) activities compared with the positive control ningnanmycin. Moreover, compound 12 strongly inhibited the expression of the TSWV N, NSs, and NSm genes and TSWV NSs protein in plant host. Furthermore, compounds 4, 10, 12, 20, and 22 exhibited moderate insecticidal activities against TSWV thrip vector (Frankliniella occidentalis). |
| 学科主题 | Agriculture ; Chemistry ; Food Science & Technology |
| WOS记录号 | WOS:000942360700001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75302]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Zhao,Li-Hua,Hu,Zhan-Xing,Hao,Xiao-Jiang,et al. Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep.[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2023,71(10):4394-4407. |
| APA | Zhao,Li-Hua.,Hu,Zhan-Xing.,Hao,Xiao-Jiang.,Zhang,Peng.,Zhang,Ji.,...&Zhang,Zhong-Kai.(2023).Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep..JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,71(10),4394-4407. |
| MLA | Zhao,Li-Hua,et al."Matrine-Type Alkaloids with Anti-Tomato Spotted Wilt Virus Activity from the Root of Sophora tonkinensis Gagnep.".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 71.10(2023):4394-4407. |
入库方式： OAI收割
来源：昆明植物研究所
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