Phytochemical Analysis and Anti-Ascaris suum Activity of Different Zanthoxylum Species In Vitro and In Vivo
文献类型：期刊论文
| 作者 | Wang,Zhao-Jie; Chen,Yi-Chi; Zou,Feng-Cai; Qin,Yan; Zhu,Yan-Yan; Xiao,Xia; Xie,Tian-Zhen; He,Ying-Jie; Zhao,Yun-li; Luo,Xiao-Dong
|
| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
 |
| 出版日期 | 2023 |
| 卷号 | 71期号:13页码:5219-5229 |
| 关键词 | Zanthoxylum plants anti-roundworm high-resolution mass spectrometry collision energy metabolites |
| ISSN号 | 1520-5118 |
| DOI | 10.1021/acs.jafc.2c08949 |
| 英文摘要 | Zanthoxylum plants (ZPs), including multiple Chinese prickly ash species, are dual-purpose functional foods favored by the general population around the world in foods, cosmetics, and traditional medicines and have antipruritic, insecticidal, and fungicidal bioactivities. For the first time, the anti-roundworm bioactivity of ZPs and the active ingredients were compared and investigated. Through nontarget metabolomics following targeted quantitative analysis, qinbunamides, sanshools, sanshooel, asarinin, and sesamin were found to be the main different components of Zanthoxylum species. Coincidentally, the 12 chemical components were also the dominant anti-roundworm ingredients of ZP extracts. The extracts of three species of Chinese prickly ash (1 mg/mL) decreased the hatchability of roundworm eggs significantly, and the ChuanJiao seed killed roundworms (insecticidal rate 100%) and alleviated the symptoms of pneumonia in mice. Furthermore, retention time-accurate mass-tandem mass spectrometry-ion ratio (RT-AM-MS/MS-IR) were modeled by assaying 108 authentic compounds of ZP extracts, and 20 metabolites were confidently identified in biological samples from ZP extract-treated mice by analyzing the m/z values and the empirical substructures. This study provides a good reference for the proper application of ZPs. |
| 学科主题 | Agriculture ; Chemistry ; Food Science & Technology |
| WOS记录号 | WOS:000959749800001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75303]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Wang,Zhao-Jie,Chen,Yi-Chi,Zou,Feng-Cai,et al. Phytochemical Analysis and Anti-Ascaris suum Activity of Different Zanthoxylum Species In Vitro and In Vivo[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2023,71(13):5219-5229. |
| APA | Wang,Zhao-Jie.,Chen,Yi-Chi.,Zou,Feng-Cai.,Qin,Yan.,Zhu,Yan-Yan.,...&Luo,Xiao-Dong.(2023).Phytochemical Analysis and Anti-Ascaris suum Activity of Different Zanthoxylum Species In Vitro and In Vivo.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,71(13),5219-5229. |
| MLA | Wang,Zhao-Jie,et al."Phytochemical Analysis and Anti-Ascaris suum Activity of Different Zanthoxylum Species In Vitro and In Vivo".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 71.13(2023):5219-5229. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。