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Five undescribed drimane-type sesquiterpenes from Polygonum hydropiper

文献类型：期刊论文

作者Wang, Chen-xi3; Li, Chen-yue2,3; Yan, Meng-kun1,3; Wang, Wen-qiong3; Xuan, Li-jiang1,3
刊名PHYTOCHEMISTRY LETTERS
出版日期2024-06-01
卷号61页码:236-241
关键词Polygonum hydropiper Drimane sesquiterpene Anti-platelet aggregation activity
ISSN号1874-3900
DOI10.1016/j.phytol.2024.05.007
通讯作者Wang, Wen-qiong(wenqiong1019@126.com) ; Xuan, Li-jiang(ljxuan@simm.ac.cn)
英文摘要In order to find various structural and active compounds, 95 % ethanol extract of P. hydropiper was investigated to obtain five undescribed drimane sesquiterpenes 3-O-angeloyl-11-O-methyldanilol ( 1 ), 3-O-tigloyl-11-O-methyldanilol ( 2 ), 3-O-(3 ' -methylbutenoyl)-11-O-methyldanilol ( 3 ), 3-O-(2 ' -metylbutanoyl)-11-O-methyldanilol ( 4 ) and 2 alpha, 3 beta-ditigloyloxy-11-O-methylisodrimeninol ( 5 ). Their structures were established by extensive spectroscopic analyses. Furthermore, 3-O-angeloyl-11-O-methyldanilol ( 1 ) showed moderate anti-platelet aggregation activity according to in vitro pharmacological evaluation.
资助项目State Key Laboratory of Drug Research, National Natural Science Foundation of China[82373746] ; Shanghai Municipal Science and Technology Major Project
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:001244651400001
出版者ELSEVIER
源URL[http://119.78.100.183/handle/2S10ELR8/311404]  
专题新药研究国家重点实验室
通讯作者Wang, Wen-qiong; Xuan, Li-jiang
作者单位1.Univ Chinese Acad Sci, Beijing 100000, Peoples R China
2.Fudan Univ, Shanghai 200000, Peoples R China
3.Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 200000, Peoples R China
推荐引用方式
GB/T 7714		 Wang, Chen-xi,Li, Chen-yue,Yan, Meng-kun,et al. Five undescribed drimane-type sesquiterpenes from Polygonum hydropiper[J]. PHYTOCHEMISTRY LETTERS,2024,61:236-241.
APA Wang, Chen-xi,Li, Chen-yue,Yan, Meng-kun,Wang, Wen-qiong,&Xuan, Li-jiang.(2024).Five undescribed drimane-type sesquiterpenes from Polygonum hydropiper.PHYTOCHEMISTRY LETTERS,61,236-241.
MLA Wang, Chen-xi,et al."Five undescribed drimane-type sesquiterpenes from Polygonum hydropiper".PHYTOCHEMISTRY LETTERS 61(2024):236-241.

入库方式： OAI收割

来源：上海药物研究所

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