Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L.
文献类型：期刊论文
| 作者 | Huang,Jian-Yi; Yang,Ying; Liang,Hong; Pu,Xue-Xue; Li,Ying-Yao; Cai,Min; Guo,Feng; Liu,Lin; Cao,Ming-Ming; Yan,Ying |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2023 |
| 卷号 | 123页码:154550 |
| 关键词 | Anti-inflammatory Pepluane Diterpenoid Euphorbia peplus L Chemical transformation DISCOVERY PARALIANE INSIGHTS PROFILE LATEX |
| ISSN号 | 1873-3581 |
| DOI | 10.1016/j.tetlet.2023.154550 |
| 英文摘要 | One new pepluane-type diterpenoid, pepluenone (1), and four known compounds were isolated from the whole plant of Euphorbia peplus L. Compound 1 possesses a 5/6/5/6 tetracyclic skeleton with a unique aromatic ring D. Its structure was determined based on spectroscopic data and X-ray crystallography. The biogenetic pathway of 1 was proposed, in which chemical transformation verified the aromatization step. In vitro anti-inflammatory activity tests indicated that Compounds 1 and 3 had a strong inhibitory effect on releasing NO from mouse macrophage RAW264.7 induced by LPS. & COPY; 2023 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry |
| WOS记录号 | WOS:001015176600001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75412]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Huang,Jian-Yi,Yang,Ying,Liang,Hong,et al. Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L.[J]. TETRAHEDRON LETTERS,2023,123:154550. |
| APA | Huang,Jian-Yi.,Yang,Ying.,Liang,Hong.,Pu,Xue-Xue.,Li,Ying-Yao.,...&Hao,Xiao-Jiang.(2023).Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L..TETRAHEDRON LETTERS,123,154550. |
| MLA | Huang,Jian-Yi,et al."Pepluenone, a new pepluane-type diterpenoid with inhibitory activity on the release of NO from the whole plant of Euphorbia peplus L.".TETRAHEDRON LETTERS 123(2023):154550. |
入库方式： OAI收割
来源：昆明植物研究所
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