Pegriseofamines A-E: Five cyclopiazonic acid related indole alkaloids from the fungus Penicillium griseofulvum
文献类型：期刊论文
| 作者 | Liang,Yu; Liao,Hong; Chen,Xuanni; Wang,Qiwei; Li,Qin; Shen,Yong; Zheng,Yuyi; Li,Xiao-Nian; Zhu,Hucheng; Li,Dongyan |
| 刊名 | BIOORGANIC CHEMISTRY
 |
| 出版日期 | 2023 |
| 卷号 | 136页码:106553 |
| 关键词 | Penicillium griseofulvum Alkaloid Cyclopiazonic acid Immunosuppression activity |
| ISSN号 | 1090-2120 |
| DOI | 10.1016/j.bioorg.2023.106553 |
| 英文摘要 | Five new cyclopiazonic acid related indole alkaloids, pegriseofamines A-E (1-5), were isolated from the fungus Penicillium griseofulvum. Their structures and absolute configurations were determined by NMR, HRESIMS, quantum-chemical calculation, and X-ray diffraction experiments. Among them, pegriseofamine A (1) possesses an undescribed 6/5/6/7 tetracyclic ring system generated by the fusion of an azepine and an indole unit via a cyclohexane, and the postulated biosynthetic origin of 1 was discussed. Compound 4 could relieve liver injury and prevent hepatocyte apoptosis in ConA-induced autoimmune liver disease. |
| 学科主题 | Biochemistry & Molecular Biology ; Chemistry |
| WOS记录号 | WOS:000991729300001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75476]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Liang,Yu,Liao,Hong,Chen,Xuanni,et al. Pegriseofamines A-E: Five cyclopiazonic acid related indole alkaloids from the fungus Penicillium griseofulvum[J]. BIOORGANIC CHEMISTRY,2023,136:106553. |
| APA | Liang,Yu.,Liao,Hong.,Chen,Xuanni.,Wang,Qiwei.,Li,Qin.,...&Zhang,Yonghui.(2023).Pegriseofamines A-E: Five cyclopiazonic acid related indole alkaloids from the fungus Penicillium griseofulvum.BIOORGANIC CHEMISTRY,136,106553. |
| MLA | Liang,Yu,et al."Pegriseofamines A-E: Five cyclopiazonic acid related indole alkaloids from the fungus Penicillium griseofulvum".BIOORGANIC CHEMISTRY 136(2023):106553. |
入库方式： OAI收割
来源：昆明植物研究所
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