Active constituents with α-glucosidase inhibitory activities from Sabia parviflora
文献类型：期刊论文
| 作者 | Hong,Qi-hui; Li,Jiang; Deng,Lu-lu; Hao,Xiao-jiang ; Mu,Shu-zhen
|
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2023 |
| 卷号 | 167页码:105516 |
| 关键词 | Sabia parviflora alpha-Glucosidase inhibitory activities Aporphine alkaloids Pentacyclic triterpenoids |
| ISSN号 | 1873-6971 |
| DOI | 10.1016/j.fitote.2023.105516 |
| 英文摘要 | To identify the active constituents with alpha-glucosidase inhibitory activities in Sabia parviflora, three new compounds, namely, sabiaparviflora A-C (1, 2 and 8), and seven known compounds were isolated from the plant by repeated column chromatography. The structures of the new compounds were identified by extensive application of spectroscopic methods, including H-1 NMR, C-13 NMR, IR and HR-ESI-MS. All compounds, except for compounds 3-5, 9 and 10 were isolated for the first time from S. parviflora. Their alpha-glucosidase inhibitory activities were evaluated for the first time by the PNPG method. Three compounds (1, 7 and 10) exhibited marked activities, with IC50 values ranging from 104 to 324 mu M, and their structure-activity relationship is preliminarily discussed herein. |
| WOS记录号 | WOS:000992059400001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75510]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Hong,Qi-hui,Li,Jiang,Deng,Lu-lu,et al. Active constituents with α-glucosidase inhibitory activities from Sabia parviflora[J]. FITOTERAPIA,2023,167:105516. |
| APA | Hong,Qi-hui,Li,Jiang,Deng,Lu-lu,Hao,Xiao-jiang,&Mu,Shu-zhen.(2023).Active constituents with α-glucosidase inhibitory activities from Sabia parviflora.FITOTERAPIA,167,105516. |
| MLA | Hong,Qi-hui,et al."Active constituents with α-glucosidase inhibitory activities from Sabia parviflora".FITOTERAPIA 167(2023):105516. |
入库方式： OAI收割
来源：昆明植物研究所
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