Prenylated acylphloroglucinols from the fruits of Garcinia xanthochymus
文献类型：期刊论文
| 作者 | Xu,Zhi-Hong; Luo,Yang; Qiu,Yu-Feng; Yang,Xing-Wei ; Lan,Tian
|
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2023 |
| 卷号 | 165页码:105427 |
| 关键词 | Garcinia xanthochymus Xanthochymusone Structural determination Cytotoxicity PHLOROGLUCINOL DERIVATIVES BENZOPHENONES XANTHONES |
| ISSN号 | 1873-6971 |
| DOI | 10.1016/j.fitote.2023.105427 |
| 英文摘要 | Our continuous study of the dry fruits of Garcinia xanthochymus led to the isolation and structural characterization of four new prenylated acylphloroglucinols, xanthochymusones J-M (1-4), together with the known polycyclic polyprenylated acylphloroglucinols, garciniagifolone A (5) and garcinialiptone A (6). Their structures were elucidated by interpretation of NMR and MS spectroscopic data. Compound 1 bearing a similar core to that of hulupinic acid should be derived via oxidization and ring contraction of prenylated acylphloroglucinol. The inhibitory activities of all the compounds against three human hepatocellular carcinoma cell lines Huh-7, Hep 3B, and Hep G2 were evaluated, and compounds 4 and 5/6 exhibited moderate cytotoxic activities against Hep G2 cells with IC50 values10.4 and 8.8 mu M. |
| 学科主题 | Pharmacology & Pharmacy |
| WOS记录号 | WOS:000923041900001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75516]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Xu,Zhi-Hong,Luo,Yang,Qiu,Yu-Feng,et al. Prenylated acylphloroglucinols from the fruits of Garcinia xanthochymus[J]. FITOTERAPIA,2023,165:105427. |
| APA | Xu,Zhi-Hong,Luo,Yang,Qiu,Yu-Feng,Yang,Xing-Wei,&Lan,Tian.(2023).Prenylated acylphloroglucinols from the fruits of Garcinia xanthochymus.FITOTERAPIA,165,105427. |
| MLA | Xu,Zhi-Hong,et al."Prenylated acylphloroglucinols from the fruits of Garcinia xanthochymus".FITOTERAPIA 165(2023):105427. |
入库方式： OAI收割
来源：昆明植物研究所
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