Steccherins A-D, chamigrane-type sesquiterpenes from the fungus Steccherinum ochraceum with selective inhibition on B lymphocyte proliferation
文献类型：期刊论文
| 作者 | Huang,Shan-Shan; Yang,Hui-Xiang; He,Juan; Yan,Bing-Chao; Feng,Tao; Liu,Ji-Kai |
| 刊名 | PHYTOCHEMISTRY
 |
| 出版日期 | 2023 |
| 卷号 | 214页码:113830 |
| 关键词 | Steccherinum ochraceum Chamigrane sesquiterpenes Steccherins A-D Immunosuppressive activity |
| ISSN号 | 1873-3700 |
| DOI | 10.1016/j.phytochem.2023.113830 |
| 英文摘要 | Four previously undescribed chamigrane sesquiterpenes, namely steccherins A-D, have been isolated from the fungus Steccherinum ochraceum. Their structures were elucidated by extensive spectroscopic analysis, as well as computational methods and single crystal X-ray diffraction. Steccherins A and B possess previously undescribed backbones which might be derived from normal chamigrane sesquiterpenes, especially that steccherin A pos-sesses a spiro[5.6]dodecane carbon skeleton via a ring-rearrangement. Steccherins A, C, and D showed immu-nosuppressive activity with IC50 values ranging from 6.2 to 37.8 mu M. The data suggested that these chamigrane sesquiterpenes have potential selective inhibition on LPS-induced B lymphocyte proliferation. |
| WOS记录号 | WOS:001144744800001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75524]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Huang,Shan-Shan,Yang,Hui-Xiang,He,Juan,et al. Steccherins A-D, chamigrane-type sesquiterpenes from the fungus Steccherinum ochraceum with selective inhibition on B lymphocyte proliferation[J]. PHYTOCHEMISTRY,2023,214:113830. |
| APA | Huang,Shan-Shan,Yang,Hui-Xiang,He,Juan,Yan,Bing-Chao,Feng,Tao,&Liu,Ji-Kai.(2023).Steccherins A-D, chamigrane-type sesquiterpenes from the fungus Steccherinum ochraceum with selective inhibition on B lymphocyte proliferation.PHYTOCHEMISTRY,214,113830. |
| MLA | Huang,Shan-Shan,et al."Steccherins A-D, chamigrane-type sesquiterpenes from the fungus Steccherinum ochraceum with selective inhibition on B lymphocyte proliferation".PHYTOCHEMISTRY 214(2023):113830. |
入库方式： OAI收割
来源：昆明植物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。