Asperidulins A and B, two new prenylxanthone derivatives from an apple-derived fungus Aspergillus nidulans KIB-HACM-01
文献类型：期刊论文
| 作者 | Lai,Peng; Wang,Li ; Deng,Chenjie; Xu,Yixin; Ma,Xiao-Yan; Cheng,Chun-Ru; Huang,Sheng-Xiong
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| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2023 |
| 关键词 | Prenylxanthones structure elucidation Aspergillus nidulans cytotoxicity |
| ISSN号 | 1478-6427 |
| DOI | 10.1080/14786419.2023.2185889 |
| 英文摘要 | Two new prenylxanthone derivatives, asperidulins A (1) and B (2), along with a known emodin analogue (3) were isolated from an apple-derived fungus Aspergillus nidulans KIB-HACM-01. Their structures were elucidated by interpretation of HRMS, NMR, and comparisons of specific optical rotation. Asperidulin B (2) exhibited a moderate cytotoxicity against A549 and BEAS-2B with an IC50 values of 13.62 +/- 0.41 and 11.27 +/- 0.52 mu M, and methyl-averantin (3) showed moderate cytotoxicities against all six tested cell lines (HL-60, A549, SMMC-7721, MDA-MB-231, SW480, BEAS-2B) with IC50 values ranging from 8.93 +/- 0.56 to 35.27 +/- 0.25 mu M. |
| 学科主题 | Chemistry ; Pharmacology & Pharmacy |
| WOS记录号 | WOS:000943867600001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75599]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Lai,Peng,Wang,Li,Deng,Chenjie,et al. Asperidulins A and B, two new prenylxanthone derivatives from an apple-derived fungus Aspergillus nidulans KIB-HACM-01[J]. NATURAL PRODUCT RESEARCH,2023. |
| APA | Lai,Peng.,Wang,Li.,Deng,Chenjie.,Xu,Yixin.,Ma,Xiao-Yan.,...&Huang,Sheng-Xiong.(2023).Asperidulins A and B, two new prenylxanthone derivatives from an apple-derived fungus Aspergillus nidulans KIB-HACM-01.NATURAL PRODUCT RESEARCH. |
| MLA | Lai,Peng,et al."Asperidulins A and B, two new prenylxanthone derivatives from an apple-derived fungus Aspergillus nidulans KIB-HACM-01".NATURAL PRODUCT RESEARCH (2023). |
入库方式： OAI收割
来源：昆明植物研究所
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