Emerging single-cell microfluidic technology for microbiology
文献类型：期刊论文
| 作者 | Y. Q. Song, J. N. Yin, W. E. Huang, B. Li and H. B. Yin |
| 刊名 | Trac-Trends in Analytical Chemistry
 |
| 出版日期 | 2024 |
| 卷号 | 170页码:17 |
| ISSN号 | 0165-9936 |
| DOI | 10.1016/j.trac.2023.117444 |
| 英文摘要 | Cell-to-cell differences exist ubiquitously in microbial communities. This individual heterogeneity, often manifested in cell phenotypic function (e.g., antibiotic resistance), can be critical in determining the fate of a microbial community. However, studying such heterogeneity in microbial communities remains a significant challenge due to their enormous diversity and complex cell-cell interactions. Here we review recent advances in microfluidic technologies for detecting, manipulating, and sorting microbial populations at the single-cell level, which significantly advanced our understanding of microbial behaviour and their roles in the microbial ecosystem. We will highlight microfluidic systems with label-free detection methods, including optical imaging and Raman spectroscopy, due to their advantages in investigating real-world microbial communities. We will showcase these technologies in emerging applications, including rapid diagnosis of pathogens and antibiotic resistance, chemotaxis, and Raman-activated cell sorting to search for natural microbial cells of desirable phenotypic function. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.ciomp.ac.cn/handle/181722/67856]  |
| 专题 | 中国科学院长春光学精密机械与物理研究所 |
| 推荐引用方式 GB/T 7714 | Y. Q. Song, J. N. Yin, W. E. Huang, B. Li and H. B. Yin. Emerging single-cell microfluidic technology for microbiology[J]. Trac-Trends in Analytical Chemistry,2024,170:17. |
| APA | Y. Q. Song, J. N. Yin, W. E. Huang, B. Li and H. B. Yin.(2024).Emerging single-cell microfluidic technology for microbiology.Trac-Trends in Analytical Chemistry,170,17. |
| MLA | Y. Q. Song, J. N. Yin, W. E. Huang, B. Li and H. B. Yin."Emerging single-cell microfluidic technology for microbiology".Trac-Trends in Analytical Chemistry 170(2024):17. |
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