Enhanced Degradability of the Apatite-Based Calcium Phosphate Cement Incorporated with Amorphous MgZnCa Alloy
文献类型：期刊论文
| 作者 | Wan, Ye2; Ma, Haoxiang2,3; Ma, Zheng3; Tan, Lili3; Miao, Lei1 |
| 刊名 | ACS BIOMATERIALS SCIENCE & ENGINEERING
 |
| 出版日期 | 2023-11-01 |
| 卷号 | 9期号:11页码:6084-6093 |
| 关键词 | Fourier transform infrared spectrometer(FTIR) calciumphosphate cement incorporation peak shift degradability |
| ISSN号 | 2373-9878 |
| DOI | 10.1021/acsbiomaterials.3c00853 |
| 通讯作者 | Wan, Ye(ywan@sjzu.edu.cn) ; Miao, Lei(miaocq777@163.com) |
| 英文摘要 | Degradability is vital for bone filling and plays an important role in bone regeneration. Evidence indicates that apatite-based calcium phosphate cement (ACPC) is a prospective biomaterial for bone repair with enhanced osteogenesis. However, poor degradability restricts their clinical application. In this study, MgZnCa-doped ACPC (MgZnCa/ACPC) composites were fabricated by adding 3 (wt) % amorphous MgZnCa powder in the solid phase of ACPC to enhance the biodegradation and bioactivity of the apatite ACPC. The chemical and the physical properties of the MgZnCa/ACPC composite were investigated and compared with the ACPC composite. The results showed that the incorporation of MgZnCa improved both the degradability and the compressive strength of the ACPC composite. X-ray diffraction and Fourier transform infrared spectrometry analysis suggested significant changes in the microstructures of the composites due to the incorporation and the anodic dissolution of MgZnCa alloy. These findings indicate that the MgZnCa/ACPC composite is capable of facilitating bone repair and regeneration by endowing favorable degradation property. |
| 资助项目 | National Natural Science Foundation of China[51971222] ; Liaoning Revitalization Talent Program[XLYC2002005] |
| WOS研究方向 | Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:001096824800001 |
| 出版者 | AMER CHEMICAL SOC |
| 资助机构 | National Natural Science Foundation of China ; Liaoning Revitalization Talent Program |
| 源URL | [http://ir.imr.ac.cn/handle/321006/177641]  |
| 专题 | 金属研究所_中国科学院金属研究所 |
| 通讯作者 | Wan, Ye; Miao, Lei |
| 作者单位 | 1.China Med Univ, Sch Stomatol, Dept Periodont & Oral Biol, Shenyang 110002, Liaoning, Peoples R China 2.Shenyang Jianzhu Univ, Sch Mat Sci & Engn, Shenyang 110168, Liaoning, Peoples R China 3.Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wan, Ye,Ma, Haoxiang,Ma, Zheng,et al. Enhanced Degradability of the Apatite-Based Calcium Phosphate Cement Incorporated with Amorphous MgZnCa Alloy[J]. ACS BIOMATERIALS SCIENCE & ENGINEERING,2023,9(11):6084-6093. |
| APA | Wan, Ye,Ma, Haoxiang,Ma, Zheng,Tan, Lili,&Miao, Lei.(2023).Enhanced Degradability of the Apatite-Based Calcium Phosphate Cement Incorporated with Amorphous MgZnCa Alloy.ACS BIOMATERIALS SCIENCE & ENGINEERING,9(11),6084-6093. |
| MLA | Wan, Ye,et al."Enhanced Degradability of the Apatite-Based Calcium Phosphate Cement Incorporated with Amorphous MgZnCa Alloy".ACS BIOMATERIALS SCIENCE & ENGINEERING 9.11(2023):6084-6093. |
入库方式： OAI收割
来源：金属研究所
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