Two new limonoid glycosides from the seeds of Citrus Limon and their PDE4D inhibitory activities
文献类型：期刊论文
| 作者 | Fu, Yifan2,3; Li, Jinlong1,3; Zhao, Weimin3
|
| 刊名 | NATURAL PRODUCT RESEARCH
 |
| 出版日期 | 2024-06-17 |
| 页码 | 7 |
| 关键词 | Citrus Limon limonoid glycosides PDE4D inhibitory activity |
| ISSN号 | 1478-6419 |
| DOI | 10.1080/14786419.2024.2370042 |
| 通讯作者 | Zhao, Weimin(wmzhao@simm.ac.cn) |
| 英文摘要 | Two new limonoid glycosides, named limonosides A (1) and B (2), along with four known limonoids (3-6) were obtained from the seeds of Citrus limon. Their structures were deduced based on extensive spectroscopic analysis. Limonoside A (1) and nomilin (4) were found to possess moderate phosphodiesterase type 4D (PDE4D) inhibitory effect with values of 89.8 +/- 2.4% and 98.9 +/- 3.0% at 10 mu M, respectively. [GRAPHICS] |
| 资助项目 | Natural Science Research Project of Jiangsu Higher Education[21KJB350004] ; Nanjing Medical University Science and Technology Development Fund[NMUB2020028] |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001253078900001 |
| 出版者 | TAYLOR & FRANCIS LTD |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/311896]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhao, Weimin |
| 作者单位 | 1.Nantong Univ, Sch Pharm, Nantong, Peoples R China 2.Nanjing Med Univ, Sch Pharm, Nanjing, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fu, Yifan,Li, Jinlong,Zhao, Weimin. Two new limonoid glycosides from the seeds of Citrus Limon and their PDE4D inhibitory activities[J]. NATURAL PRODUCT RESEARCH,2024:7. |
| APA | Fu, Yifan,Li, Jinlong,&Zhao, Weimin.(2024).Two new limonoid glycosides from the seeds of Citrus Limon and their PDE4D inhibitory activities.NATURAL PRODUCT RESEARCH,7. |
| MLA | Fu, Yifan,et al."Two new limonoid glycosides from the seeds of Citrus Limon and their PDE4D inhibitory activities".NATURAL PRODUCT RESEARCH (2024):7. |
入库方式： OAI收割
来源：上海药物研究所
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