Fetal exposure to organic contaminants revealed by infant hair: A preliminary study in south China*
文献类型：期刊论文
| 作者 | Cai, Feng-Shan4,5,6; Tang, Bin5; Zheng, Jing3,5; Yan, Xiao3,5; Luo, Wei-Keng5; He, Mian2; Luo, Xiao-Jun1,6; Ren, Ming-Zhong5; Yu, Yun-Jiang5; Mai, Bi-Xian1,6 |
| 刊名 | ENVIRONMENTAL POLLUTION
 |
| 出版日期 | 2023 |
| 卷号 | 316页码:7 |
| 关键词 | Infant hair Maternal hair Organic contaminants Fetal exposure Birth size |
| ISSN号 | 0269-7491 |
| DOI | 10.1016/j.envpol.2022.120536 |
| 英文摘要 | Fetal exposure to multiple organic contaminants (OCs) is a public concern because of the adverse effects of OCs on early life development. Infant hair has the potential to be used as an alternative matrix to identify susceptible fetuses, owing to its reliability, sensitivity, and advantages associated with sampling, handling, and ethics. However, the applicability of infant hair for assessing in utero exposure to OCs is still limited. In this study, 57 infant hair samples were collected in Guangzhou, South China, to evaluate the levels and compositions of typical OCs in the fetus. Most of the target OCs were detected in infant hair, with medians of 144 mu g/g, 17.7 mu g/g, 192 ng/g, 46.9 ng/g, and 1.36 ng/g for phthalate esters (PAEs), alternative plasticizers (APs), organophosphorus flame retardants (OPFRs), polybrominated diphenyl ethers (PBDEs), and organochlorine pesticides (OCPs), respectively. Meanwhile, paired maternal hair (0-9 cm from the scalp) was collected to examine the associations between maternal and infant hair for individual compounds. Low-brominated PBDEs tended to deposit in infant hair, with median concentrations approximately two times higher than those in maternal samples. Levels of PBDEs and 4,4 '-dichlorodiphenyldichloroethylene (p,p'-DDE) in paired maternal and infant hair showed strong positive correlations (p < 0.05), while most plasticizers (PAEs and APs) were poorly correlated between paired hair samples. Exposure sources were responsible for the variation in correlation between OC levels in the paired infant and maternal samples. Crude relationships between fetal exposure to OCs and birth size were examined using the Bayesian kernel machine regression (BKMR) model. BDE-28 was found to be adversely associated with the birth size. This study provides referential information for evaluating in utero exposure to OCs and their health risks based on infant hair. |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000904790400008 |
| 源URL | [http://ir.gig.ac.cn/handle/344008/71549]  |
| 专题 | 有机地球化学国家重点实验室 |
| 通讯作者 | Zheng, Jing |
| 作者单位 | 1.Chinese Acad Sci, Guangzhou Inst Geochem, Guangdong Hong Kong Macao Joint Lab Environm Pollu, Guangzhou 510640, Peoples R China 2.Sun Yat Sen Univ, Affiliated Hosp 7, Guangdong Prov Key Lab Digest Canc Res, Shenzhen 518107, Peoples R China 3.Guizhou Med Univ, Sch Publ Hlth, Key Lab Environm Pollut & Dis Monitoring, Minist Educ, Guiyang 550000, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Minist Environm Protect, South China Inst Environm Sci, State Environm Protect Key Lab Environm Pollut Hlt, Guangzhou 510655, Peoples R China 6.Chinese Acad Sci, Guangzhou Inst Geochem, State Key Lab Organ Geochem, Guangdong Prov Key Lab Environm Protect & Resource, Guangzhou 510640, Peoples R China |
| 推荐引用方式 GB/T 7714 | Cai, Feng-Shan,Tang, Bin,Zheng, Jing,et al. Fetal exposure to organic contaminants revealed by infant hair: A preliminary study in south China*[J]. ENVIRONMENTAL POLLUTION,2023,316:7. |
| APA | Cai, Feng-Shan.,Tang, Bin.,Zheng, Jing.,Yan, Xiao.,Luo, Wei-Keng.,...&Mai, Bi-Xian.(2023).Fetal exposure to organic contaminants revealed by infant hair: A preliminary study in south China*.ENVIRONMENTAL POLLUTION,316,7. |
| MLA | Cai, Feng-Shan,et al."Fetal exposure to organic contaminants revealed by infant hair: A preliminary study in south China*".ENVIRONMENTAL POLLUTION 316(2023):7. |
入库方式： OAI收割
来源：广州地球化学研究所
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