Complex polycyclic aromatic compound mixtures in PM2.5 in a Chinese megacity: Spatio-temporal variations, toxicity, and source apportionment
文献类型：期刊论文
| 作者 | Zeng, Yuan2; Ma, Hui-Min1; Zhang, Qian-Yu1,4; Tao, Lin3; Wang, Tao5; Wan, Cong1,4; Chen, She-Jun2; Mai, Bi-Xian1 |
| 刊名 | ENVIRONMENT INTERNATIONAL
 |
| 出版日期 | 2023-09-01 |
| 卷号 | 179页码:9 |
| 关键词 | Polycyclic aromatic hydrocarbons (PAHs) High molecular weight PAHs (MW302 PAHs) Oxygenated PAHs (OPAHs) Nitrated PAHs (NPAHs) Reactive oxygen species (ROS) Cell mortality |
| ISSN号 | 0160-4120 |
| DOI | 10.1016/j.envint.2023.108159 |
| 英文摘要 | Polycyclic aromatic compounds (PACs) are important toxic organic components in fine particulate matter (PM2.5), whereas the links between PM2.5 toxicity and associated PACs in ambient air are poorly understood. This study investigated the spatial-temporal variations of PACs in PM2.5 collected from 11 sampling sites across a Chinese megacity and characterized the reactive oxygen species (ROS) generation and cytotoxicity induced by organic extracts of PM2.5 based on cellular assays. The extra trees regression model based on machine learning and ridge regression were used to identify the key toxicants among complex PAC mixtures. The total concentrations of these PACs varied from 2.12 to 71.7 ng/m(3) across the study city, and polycyclic aromatic hydrocarbons (PAHs) are the main PACs. The spatial variations of the toxicological indicators generally resembled those of the PAC concentrations, and the PM2.5 related to waste treatment facilities exhibited the strongest toxic potencies. The ROS generation was highly correlated with high molecular weight PAHs (MW302 PAHs), followed by PAHs with MW<302 amu and oxygenated PAHs, but not with nitrated PAHs and the plastics additives. The cell mortality showed weak correlations with these organic constituents. The associations between the biological endpoints and these PM2.5-bound contaminants were further confirmed by exposure to authentic chemicals. Four primary sources of PACs were identified, among which coal and biomass combustion sources (30.2% of the total PACs) and industrial sources (31.0%) were predominant. PACs emitted from industrial sources were highly associated with ROS generation in this city. Our findings highlight the potent ROS-generating potential of MW302 PAHs and the importance of industrial sources contributing to PM2.5 toxicity in this megacity, raising public concerns and further administration. |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:001064287700001 |
| 源URL | [http://ir.gig.ac.cn/handle/344008/74890]  |
| 专题 | 有机地球化学国家重点实验室 |
| 通讯作者 | Chen, She-Jun |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Organ Geochem & Guangdong Prov, Key Lab Environm Protect & Resources Utilizat, Guangzhou Inst Geochem, Guangzhou 510640, Peoples R China 2.South China Normal Univ, Sch Environm, Guangdong Prov Key Lab Chem Pollut & Environm Safe, MOE Key Lab Theoret Chem Environm, Guangzhou 510006, Peoples R China 3.Anhui Med Univ, Sch Publ Hlth, Dept Toxicol, Hefei 230032, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Chinese Res Inst Environm Sci, Beijing 100012, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zeng, Yuan,Ma, Hui-Min,Zhang, Qian-Yu,et al. Complex polycyclic aromatic compound mixtures in PM2.5 in a Chinese megacity: Spatio-temporal variations, toxicity, and source apportionment[J]. ENVIRONMENT INTERNATIONAL,2023,179:9. |
| APA | Zeng, Yuan.,Ma, Hui-Min.,Zhang, Qian-Yu.,Tao, Lin.,Wang, Tao.,...&Mai, Bi-Xian.(2023).Complex polycyclic aromatic compound mixtures in PM2.5 in a Chinese megacity: Spatio-temporal variations, toxicity, and source apportionment.ENVIRONMENT INTERNATIONAL,179,9. |
| MLA | Zeng, Yuan,et al."Complex polycyclic aromatic compound mixtures in PM2.5 in a Chinese megacity: Spatio-temporal variations, toxicity, and source apportionment".ENVIRONMENT INTERNATIONAL 179(2023):9. |
入库方式： OAI收割
来源：广州地球化学研究所
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