Secondary Organic Aerosol Generated from Biomass Burning Emitted Phenolic Compounds: Oxidative Potential, Reactive Oxygen Species, and Cytotoxicity
文献类型：期刊论文
| 作者 | Fang, Zheng1; Lai, Alexandra1; Cai, Dongmei6; Li, Chunlin1,5; Carmieli, Raanan4; Chen, Jianmin6; Wang, Xinming2,3; Rudich, Yinon1 |
| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
 |
| 出版日期 | 2024-04-29 |
| 卷号 | 58期号:19页码:8194-8206 |
| 关键词 | phenolic compounds secondary organic aerosol oxidative potential reactive oxygen species cytotoxicity |
| ISSN号 | 0013-936X |
| DOI | 10.1021/acs.est.3c09903 |
| 英文摘要 | Phenolic compounds are largely emitted from biomass burning (BB) and have a significant potential to form SOA (Phc-SOA). However, the toxicological properties of Phc-SOA remain unclear. In this study, phenol and guaiacol were chosen as two representative phenolic gases in BB plumes, and the toxicological properties of water-soluble components of their SOA generated under different photochemical ages and NOx levels were investigated. Phenolic compounds contribute greatly to the oxidative potential (OP) of biomass-burning SOA. OH-adducts of guaiacol (e.g., 2-methoxyhydroquinone) were identified as components of guaiacol SOA (GSOA) with high OP. The addition of nitro groups to 2,5-dimethyl-1,4-benzoquinone, a surrogate quinone compound in Phc-SOA, increased its OP. The toxicity of both phenol SOA (PSOA) and GSOA in vitro in human alveolar epithelial cells decreased with aging in terms of both cell death and cellular reactive oxygen species (ROS), possibly due to more ring-opening products with relatively low toxicity. The influence of NOx was consistent between cell death and cellular ROS for GSOA but not for PSOA, indicating that cellular ROS production does not necessarily represent all processes contributing to cell death caused by PSOA. Combining different acellular and cellular assays can provide a comprehensive understanding of aerosol toxicological properties. |
| WOS研究方向 | Engineering ; Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:001228014400001 |
| 源URL | [http://ir.gig.ac.cn/handle/344008/78570]  |
| 专题 | 有机地球化学国家重点实验室 |
| 通讯作者 | Fang, Zheng; Rudich, Yinon |
| 作者单位 | 1.Weizmann Inst Sci, Dept Earth & Planetary Sci, IL-76100 Rehovot, Israel 2.Chinese Acad Sci, Guangzhou Inst Geochem, Guangdong Key Lab Environm Protect & Resources Uti, Guangzhou 510640, Peoples R China 3.Chinese Acad Sci, Guangzhou Inst Geochem, State Key Lab Organ Geochem, Guangzhou 510640, Peoples R China 4.Weizmann Inst Sci, Dept Chem Res Support, IL-76100 Rehovot, Israel 5.Tongji Univ, Coll Environm Sci & Engn, Shanghai 200072, Peoples R China 6.Fudan Univ, Dept Environm Sci & Engn, Shanghai Key Lab Atmospher Particle Pollut & Preve, Shanghai 200438, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fang, Zheng,Lai, Alexandra,Cai, Dongmei,et al. Secondary Organic Aerosol Generated from Biomass Burning Emitted Phenolic Compounds: Oxidative Potential, Reactive Oxygen Species, and Cytotoxicity[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2024,58(19):8194-8206. |
| APA | Fang, Zheng.,Lai, Alexandra.,Cai, Dongmei.,Li, Chunlin.,Carmieli, Raanan.,...&Rudich, Yinon.(2024).Secondary Organic Aerosol Generated from Biomass Burning Emitted Phenolic Compounds: Oxidative Potential, Reactive Oxygen Species, and Cytotoxicity.ENVIRONMENTAL SCIENCE & TECHNOLOGY,58(19),8194-8206. |
| MLA | Fang, Zheng,et al."Secondary Organic Aerosol Generated from Biomass Burning Emitted Phenolic Compounds: Oxidative Potential, Reactive Oxygen Species, and Cytotoxicity".ENVIRONMENTAL SCIENCE & TECHNOLOGY 58.19(2024):8194-8206. |
入库方式： OAI收割
来源：广州地球化学研究所
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