Unravelling biosynthesis and biodegradation potentials of microbial dark matters in hypersaline lakes
文献类型：期刊论文
| 作者 | Qiu, Zhiguang2,3; Zhu, Yuanyuan2; Zhang, Qing2; Qiao, Xuejiao2; Mu, Rong2; Xu, Zheng4,5; Yan, Yan6; Wang, Fan7; Zhang, Tong8; Zhuang, Wei-Qin1 |
| 刊名 | ENVIRONMENTAL SCIENCE AND ECOTECHNOLOGY
 |
| 出版日期 | 2024-07-01 |
| 卷号 | 20页码:12 |
| 关键词 | Biosynthesis Biodegradation Hypersaline lakes Metagenome-assembled genomes Microbial dark matters |
| ISSN号 | 2666-4984 |
| DOI | 10.1016/j.ese.2023.100359 |
| 英文摘要 | Biosynthesis and biodegradation of microorganisms critically underpin the development of biotechnology, new drugs and therapies, and environmental remediation. However, most uncultured microbial species along with their metabolic capacities in extreme environments, remain obscured. Here we un-ravel the metabolic potential of microbial dark matters (MDMs) in four deep-inland hypersaline lakes in Xinjiang, China. Utilizing metagenomic binning, we uncovered a rich diversity of 3030 metagenome-assembled genomes (MAGs) across 82 phyla, revealing a substantial portion, 2363 MAGs, as previously unclassified at the genus level. These unknown MAGs displayed unique distribution patterns across different lakes, indicating a strong correlation with varied physicochemical conditions. Our analysis revealed an extensive array of 9635 biosynthesis gene clusters (BGCs), with a remarkable 9403 being novel, suggesting untapped biotechnological potential. Notably, some MAGs from potentially new phyla exhibited a high density of these BGCs. Beyond biosynthesis, our study also identified novel biodegradation pathways, including dehalogenation, anaerobic ammonium oxidation (Anammox), and degradation of polycyclic aromatic hydrocarbons (PAHs) and plastics, in previously unknown microbial clades. These findings significantly enrich our understanding of biosynthesis and biodegradation processes and open new avenues for biotechnological innovation, emphasizing the untapped potential of microbial diversity in hypersaline environments.(c) 2023 The Authors. Published by Elsevier B.V. on behalf of Chinese Society for Environmental Sciences, Harbin Institute of Technology, Chinese Research Academy of Environmental Sciences. |
| WOS研究方向 | Science & Technology - Other Topics ; Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:001149678600001 |
| 源URL | [http://ir.gig.ac.cn/handle/344008/76179]  |
| 专题 | 同位素地球化学国家重点实验室 |
| 通讯作者 | Yu, Ke |
| 作者单位 | 1.Univ Auckland, Fac Engn, Dept Civil & Environm Engn, Auckland, New Zealand 2.Peking Univ, Grad Sch, Sch Environm & Energy, Shenzhen 518055, Peoples R China 3.Peking Univ, AI Sci AI4S Preferred Program, Shenzhen 518055, Peoples R China 4.Southern Univ Sci & Technol, Yantian Hosp, Shenzhen 518081, Peoples R China 5.Chinese Acad Sci, Inst Biomed & Biotechnol, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China 6.Chinese Acad Sci, Guangzhou Inst Geochem, CAS Ctr Excellence Deep Earth Sci, State Key Lab Isotope Geochem, Guangzhou 510640, Peoples R China 7.Sun Yat Sen Univ, Sch Atmospher Sci, Southern Marine Sci & Engn Guangdong Lab Zhuhai, Zhuhai 519082, Peoples R China 8.Univ Hong Kong, Dept Civil Engn, Hong Kong 999077, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiu, Zhiguang,Zhu, Yuanyuan,Zhang, Qing,et al. Unravelling biosynthesis and biodegradation potentials of microbial dark matters in hypersaline lakes[J]. ENVIRONMENTAL SCIENCE AND ECOTECHNOLOGY,2024,20:12. |
| APA | Qiu, Zhiguang.,Zhu, Yuanyuan.,Zhang, Qing.,Qiao, Xuejiao.,Mu, Rong.,...&Yu, Ke.(2024).Unravelling biosynthesis and biodegradation potentials of microbial dark matters in hypersaline lakes.ENVIRONMENTAL SCIENCE AND ECOTECHNOLOGY,20,12. |
| MLA | Qiu, Zhiguang,et al."Unravelling biosynthesis and biodegradation potentials of microbial dark matters in hypersaline lakes".ENVIRONMENTAL SCIENCE AND ECOTECHNOLOGY 20(2024):12. |
入库方式： OAI收割
来源：广州地球化学研究所
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