Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347
文献类型：期刊论文
| 作者 | Li, Xiao-Dong1,2,4 ; Li, Xiao-Ming4; Wang, Bin-Gui2,3,4; Li, Xin3,4
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| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
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| 出版日期 | 2024-04-29 |
| 页码 | 7 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/d4ob00449c |
| 通讯作者 | Wang, Bin-Gui(wangbg@ms.qdio.ac.cn) ; Li, Xin(lixin@qdio.ac.cn) |
| 英文摘要 | Two new sesterterpenoids, sesterchaetins A and B (1 and 2), and two new diepoxide polyketides, chaetoketoics A and B (3 and 4), were characterized from the culture extract of Chaetomium globosum SD-347, a fungal strain derived from deep sea-sediment. Their structures and absolute configurations were unambiguously determined by detailed NMR, mass spectra, and X-ray crystallographic analysis. Compounds 1 and 2 contained a distinctive 5/8/6/5 tetracyclic carbon-ring-system, which represented a rarely occurring natural product framework. The new isolates 1-4 exhibited selective antimicrobial activities against human and aquatic pathogenic bacteria and plant-pathogenic fungi. |
| WOS关键词 | ENDOPHYTIC FUNGUS ; NATURAL-PRODUCTS ; A-D ; METABOLITES ; CHAETOGLOBOSIN ; GENES |
| 资助项目 | Qingdao National Laboratory for Marine Science and Technology[2022QNLM030004-4] ; Shandong Special Fund for Qingdao National Laboratory for Marine Science and Technology[42076090] ; Shandong Special Fund for Qingdao National Laboratory for Marine Science and Technology[U2006203] ; Shandong Special Fund for Qingdao National Laboratory for Marine Science and Technology[KEXUE2020GZ02] ; National Natural Science Foundation of China[ZR2021ZD28] ; National Natural Science Foundation of China[ZR2019ZD18] ; Shandong Provincial Natural Science Foundation[2023216] ; Youth Innovation Promotion Association CAS ; National Major Science and Technology Infrastructure from the Chinese Academy of Sciences |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001216632600001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/185628]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Wang, Bin-Gui; Li, Xin |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Chunhui Rd 17, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China 3.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Wenhai Rd 1, Qingdao 266237, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, CAS & Shandong Prov Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xiao-Dong,Li, Xiao-Ming,Wang, Bin-Gui,et al. Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2024:7. |
| APA | Li, Xiao-Dong,Li, Xiao-Ming,Wang, Bin-Gui,&Li, Xin.(2024).Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347.ORGANIC & BIOMOLECULAR CHEMISTRY,7. |
| MLA | Li, Xiao-Dong,et al."Antimicrobial sesterterpenoids with a unique 5/8/6/5 tetracyclic carbon-ring-system and diepoxide polyketides from a deep sea-sediment-sourced fungus Chaetomium globosum SD-347".ORGANIC & BIOMOLECULAR CHEMISTRY (2024):7. |
入库方式： OAI收割
来源：海洋研究所
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