Evaluation of the chronic toxicity of bisphenol A and bisphenol AF to sea cucumber Apostichopus japonicus after long-term single and combined exposure at environmental relevant concentration
文献类型：期刊论文
| 作者 | Lai, Kaiqi2,3,4 ; Zhang, Libin2,3,4; Xu, Jialei1
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| 刊名 | ENVIRONMENTAL RESEARCH
 |
| 出版日期 | 2024-06-15 |
| 卷号 | 251页码:10 |
| 关键词 | Bisphenol Endocrine disruptor Histological alterations Integrated biomarker response Sea cucumbers |
| ISSN号 | 0013-9351 |
| DOI | 10.1016/j.envres.2024.118748 |
| 通讯作者 | Zhang, Libin(zhanglibin@qdio.ac.cn) |
| 英文摘要 | Bisphenols are emerging endocrine disrupting pollutant, and several studies have reported that they are already ubiquitous in various environmental matrices and intend to deposit in sediment. The primary sources of bisphenols are river and sewage discharge. Sea cucumber ( Apostichopus japonicus ), a typical deposit feeder, is one of the most important commercial marine species in Aisa. However, the effects of the bisphenol A (BPA) and its analogues bisphenol AF (BPAF) on sea cucumber was unclear. In this study, we carried out field survey in major sea cucumber farming areas in northern China, with the aim of determining which bisphenol analogue is the major bisphenol contamination in this aquaculture area. The results showed that the presence of BPAF was detected in four sampling sites (Dalian, Tangshan, Laizhou, and Longpan). The mean level of BPAF in Laizhou sediment samples was the highest which reached to 9.007 +/- 4.702 mu g/kg. Among the seawater samples, the BPAF only have been detected in the samples collected at Longpan. (0.011 +/- 0.003 mu g/L). Furthermore, we conducted an experiment to evaluate the single and combined toxicity of BPA and BPAF on sea cucumbers. The concentrations were informed by the findings based on the results of field research. (0.1, 1.0, and 10 mu g/L). After exposure, the body weight gain, and specific growth rate showed no significant changes ( P > 0.05). We observed the histological alterations in respiratory tree of treated sea cucumbers including the fusion and detachment of lining epithelial tissue, and increase of lumen space. However, the catalase (CAT), malondialdehyde (MDA), and glutathione (GSH) activity was not significantly changed ( P > 0.05). We evaluated the effects of BPA and BPAF through calculating the integrated biomarker response index (IBR), and the results indicated that the toxicity of combined treatment was higher than single treatment. Additionally, BPAF exposure to A . japonicus was more toxic than BPA. |
| WOS关键词 | INTEGRATED BIOMARKER RESPONSE ; SEDIMENTS ; ACCUMULATION ; REPRODUCTION ; GROWTH |
| 资助项目 | National Key Research and Devel-opment Program of China[2023YFD2401105] |
| WOS研究方向 | Environmental Sciences & Ecology ; Public, Environmental & Occupational Health |
| 语种 | 英语 |
| WOS记录号 | WOS:001223325500001 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/185790]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Zhang, Libin |
| 作者单位 | 1.Shandong Tonhe Ocean Technol Co Ltd, Dongying 257200, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Inst Oceanol, Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lai, Kaiqi,Zhang, Libin,Xu, Jialei. Evaluation of the chronic toxicity of bisphenol A and bisphenol AF to sea cucumber Apostichopus japonicus after long-term single and combined exposure at environmental relevant concentration[J]. ENVIRONMENTAL RESEARCH,2024,251:10. |
| APA | Lai, Kaiqi,Zhang, Libin,&Xu, Jialei.(2024).Evaluation of the chronic toxicity of bisphenol A and bisphenol AF to sea cucumber Apostichopus japonicus after long-term single and combined exposure at environmental relevant concentration.ENVIRONMENTAL RESEARCH,251,10. |
| MLA | Lai, Kaiqi,et al."Evaluation of the chronic toxicity of bisphenol A and bisphenol AF to sea cucumber Apostichopus japonicus after long-term single and combined exposure at environmental relevant concentration".ENVIRONMENTAL RESEARCH 251(2024):10. |
入库方式： OAI收割
来源：海洋研究所
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