Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium
文献类型：期刊论文
| 作者 | Li, Kehan1,3,4,5; Wang, Fayuan1; Liu, Shuai2; Cheng, Xiaochen1,3,4,5; Xu, Jialei6; Liu, Xiao6; Zhang, Libin3,4,5 |
| 刊名 | MARINE POLLUTION BULLETIN
 |
| 出版日期 | 2024-07-01 |
| 卷号 | 204页码:12 |
| 关键词 | Polystyrene microplastics (PS-MPs) Cadmium (cd) Combined anthropogenic stresses Metabolomics Apostichopus japonicus |
| ISSN号 | 0025-326X |
| DOI | 10.1016/j.marpolbul.2024.116519 |
| 通讯作者 | Zhang, Libin(zhanglibin@qdio.ac.cn) |
| 英文摘要 | Microplastics (MPs) have become pervasive in marine ecosystems, exerting detrimental effects on marine life. The concurrent presence and interaction of MPs and heavy metals in aquatic environments could engender more insidious toxicological impacts. This study aimed to elucidate the potential impacts and underlying mechanisms of polystyrene microplastics (PS-MPs), cadmium (Cd), and their combined stress (MPs-Cd) on sea cucumbers (Apostichopus japonicus). It focused on the growth, Cd bioaccumulation, oxidative stress responses, immunoenzymatic activities, and metabolic profiles, specifically considering PS-MPs sizes preferentially ingested by these organisms. The high-dose MPs (MH) treatment group exhibited an increase in cadmium bioavailability within the sea cucumbers. Exposure to PS-MPs or Cd triggered the activation of antioxidant defenses and immune responses. PS-MPs and Cd exhibited a synergistic effect on lysozyme (LZM) activity. A total of 149, 316, 211, 197, 215, 619, 434, and 602 differentially expressed metabolites were identified, distinguishing the low-dose MPs (ML), high-dose MPs (MH), low-dose Cd (LCd), low-dose MPs and low-dose Cd (MLLCd), high-dose MPs and low-dose Cd (MHLCd), high-dose Cd (HCd), low-dose MPs and high-dose Cd (MLHCd), high-dose MPs and high-dose Cd (MHHCd) groups, respectively. Metabolomic analyses revealed disruptions in lipid metabolism, nervous system function, signal transduction, and transport and catabolism pathways following exposure to PSMPs, Cd, and MPs-Cd. Correlation analyses among key differentially expressed metabolites (DEMs) underscored the interregulation among these metabolic pathways. These results offer new perspectives on the distinct and synergistic toxicological impacts of microplastics and cadmium on aquatic species, highlighting the complex interplay between environmental contaminants and their effects on marine life. |
| WOS关键词 | HEAVY-METAL POLLUTION ; TRACE-METALS ; SEA ; BIOACCUMULATION ; ACCUMULATION ; ADSORPTION ; SEDIMENTS ; WATER |
| 资助项目 | National Key Research and Devel- opment Program of China[2023YFD2401105] |
| WOS研究方向 | Environmental Sciences & Ecology ; Marine & Freshwater Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:001263752600001 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/186305]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Zhang, Libin |
| 作者单位 | 1.Qingdao Univ Sci & Technol, Coll Environm & Safety Engn, Qingdao 266042, Peoples R China 2.Binzhou Ocean Dev Res Inst, Binzhou 256600, Peoples R China 3.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, CAS Engn Lab Marine Ranching, Qingdao 266071, Peoples R China 6.Zhongke Tonghe Shandong Ocean Technol Co Ltd, Dongying 257200, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Kehan,Wang, Fayuan,Liu, Shuai,et al. Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium[J]. MARINE POLLUTION BULLETIN,2024,204:12. |
| APA | Li, Kehan.,Wang, Fayuan.,Liu, Shuai.,Cheng, Xiaochen.,Xu, Jialei.,...&Zhang, Libin.(2024).Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium.MARINE POLLUTION BULLETIN,204,12. |
| MLA | Li, Kehan,et al."Response and adaptation mechanisms of Apostichopus japonicus to single and combined anthropogenic stresses of polystyrene microplastics or cadmium".MARINE POLLUTION BULLETIN 204(2024):12. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。