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First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field

文献类型：期刊论文

作者Wei, Zechen1,2; Liu, Yanjun3,4,5,6; Liu, Sijia6; Yu, Xiaomei7,8; Zhang, Haoran3,4,5,6; Zhu, Tao1,2; Zhang, Bo3,4,5,6; Zhang, Yali7,8; Huang, Hongdi7,8; Fan, Yang7,8
刊名IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
出版日期2024
卷号73页码:11
关键词Coils Imaging Three-dimensional displays Magnetic fields Sensitivity Spatial resolution Permanent magnets Digital scanned focus field magnetic particle imaging (MPI) nonhuman primate (NHP)
ISSN号0018-9456
DOI10.1109/TIM.2024.3418109
通讯作者Wang, Jianhong(wangjh@mail.kiz.ac.cn) ; Tian, Jie(tian@ieee.org) ; Hui, Hui(hui.hui@ia.ac.cn)
英文摘要Magnetic particle imaging (MPI) is a burgeoning imaging modality that facilitates the reconstruction of position and concentration of superparamagnetic iron oxide nanoparticles. Its potential in clinical applications is substantial, leading to an increasing demand for larger bore sizes in MPI systems. However, the challenge lies in maintaining high resolution, sensitivity, and real-time imaging advantages in larger systems. In this article, we present the design of a 3-D MPI system tailored for nonhuman primates (NHP-MPI) with a bore size of 190 mm. The application of a 3-D digital-scanned focus field is applied to obtain highly sensitive imaging, and the system operates cooling-free under low gradient conditions. In imaging experiments involving a macaque's brain, our system demonstrated good quantitative performance. The 3-D MPI image yielded satisfactory results for fusion with other structural imaging modalities.
资助项目National Key Research and Development Program of China[2021YFF0702700] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[92359304] ; National Natural Science Foundation of China[U23A6011] ; National Natural Science Foundation of China[81930053] ; National Natural Science Foundation of China[81227901] ; Beijing Natural Science Foundation[JQ22023] ; Chinese Academy of Sciences(CAS) Youth Innovation Promotion Association[Y2022055] ; STI2030-Major Projects[2021ZD0203900] ; STI2030-Major Projects[2022ZD0205100] ; Yunnan Province[202305AH340006]
WOS研究方向Engineering ; Instruments & Instrumentation
语种英语
WOS记录号WOS:001263442300010
出版者IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
资助机构National Key Research and Development Program of China ; National Natural Science Foundation of China ; Beijing Natural Science Foundation ; Chinese Academy of Sciences(CAS) Youth Innovation Promotion Association ; STI2030-Major Projects ; Yunnan Province
源URL[http://ir.ia.ac.cn/handle/173211/59196]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Wang, Jianhong; Tian, Jie; Hui, Hui
作者单位1.Chinese Acad Sci, Inst Automat, Sch Artificial Intelligence, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100190, Peoples R China
3.Beihang Univ, Key Lab Big Data Based Precis Med, Beijing 100190, Peoples R China
4.Beihang Univ, Sch Engn Med, Beijing 100190, Peoples R China
5.Beihang Univ, Sch Biol Sci & Med Engn, Beijing 100190, Peoples R China
6.Southeast Univ, Sch Comp Sci & Engn, Nanjing 210000, Peoples R China
7.Chinese Acad Sci, Kunming Inst Zool, Natl Resource Ctr Nonhuman Primates, Kunming Primate Res Ctr, Kunming 650000, Peoples R China
8.Chinese Acad Sci, Kunming Inst Zool, Natl Res Facil Phenotyp & Genet Anal Model Anim Pr, Kunming 650000, Peoples R China
9.Beihang Univ, Sch Engn Med, Key Lab Big Data Based Precis Med, Minist Ind & Informat Technol Peoples Republ China, Beijing 100190, Peoples R China
10.Beihang Univ, Sch Biol Sci & Med Engn, Beijing 100190, Peoples R China
推荐引用方式
GB/T 7714		 Wei, Zechen,Liu, Yanjun,Liu, Sijia,et al. First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field[J]. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,2024,73:11.
APA Wei, Zechen.,Liu, Yanjun.,Liu, Sijia.,Yu, Xiaomei.,Zhang, Haoran.,...&Hui, Hui.(2024).First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field.IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,73,11.
MLA Wei, Zechen,et al."First Nonhuman Primate-Sized Magnetic Particle Imaging System Based on Digital-Scanned Focus Field".IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT 73(2024):11.

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来源：自动化研究所

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