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Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2

文献类型：期刊论文

作者Zheng, Miao6,8; Feng, Bo5,7; Zhang, Yumin4; Liu, Xin6; Zhao, Na6,8; Liu, Hui5; Xu, Zichao6; He, Xinheng6; Qu, Zhiyan6; Chen, Shizhao5
刊名ACTA PHARMACEUTICA SINICA B
出版日期2024-07-01
卷号14期号:7页码:3286-3290
关键词Non-covalent PLpro inhibitors Antiviral activity Structural-based drug design Imidazo[4,5-b]pyridine scaffold
ISSN号2211-3835
DOI10.1016/j.apsb.2024.04.011
通讯作者Zhao, Lin- xiang(linxiang.zhao@vip.sina.com) ; Zheng, Jie(jzheng@simm.ac.cn) ; Zhang, Leike(zhangleike@wh.iov.cn) ; Li, Jia(linxiang.zhao@vip.sina.com) ; Zhou, Yu(zhouyu@simm.ac.cn)
资助项目National Natural Science Foundation of China[82151219] ; National Natural Science Foundation of China[82130105] ; Strategic Priority Research Program of Chinese Academy of Sciences[SIMM010109] ; Strategic Priority Research Program of Chinese Academy of Sciences[SIMM010111] ; Shanghai Institute of Materia Medica of Chinese Academy of Sciences[SIMM0120231003]
WOS研究方向Pharmacology & Pharmacy
语种英语
WOS记录号WOS:001265911700001
出版者INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES
源URL[http://119.78.100.183/handle/2S10ELR8/312249]  
专题中国科学院上海药物研究所
通讯作者Zhao, Lin- xiang; Zheng, Jie; Zhang, Leike; Li, Jia; Zhou, Yu
作者单位1.Hubei Jiangxia Lab, Wuhan 430200, Peoples R China
2.Univ Chinese Acad Sci, Hangzhou Inst Adv Study, Sch Pharmaceut Sci & Technol, Hangzhou 310024, Peoples R China
3.Lingang Lab, Shanghai 200031, Peoples R China
4.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Ctr Biosafety Mega Sci, Wuhan 430071, Peoples R China
5.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Chem Biol, Shanghai 201203, Peoples R China
6.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
7.Shenyang Pharmaceut Univ, Sch Life Sci & Biopharmaceut, Shenyang 110016, Peoples R China
8.Shenyang Pharmaceut Univ, Key Lab Struct Based Drugs Design & Discovery, Minist Educ, Shenyang 110016, Peoples R China
推荐引用方式
GB/T 7714		 Zheng, Miao,Feng, Bo,Zhang, Yumin,et al. Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2[J]. ACTA PHARMACEUTICA SINICA B,2024,14(7):3286-3290.
APA Zheng, Miao.,Feng, Bo.,Zhang, Yumin.,Liu, Xin.,Zhao, Na.,...&Zhou, Yu.(2024).Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2.ACTA PHARMACEUTICA SINICA B,14(7),3286-3290.
MLA Zheng, Miao,et al."Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2".ACTA PHARMACEUTICA SINICA B 14.7(2024):3286-3290.

入库方式： OAI收割

来源：上海药物研究所

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