A high-quality chromosomal genome assembly of the sea cucumber Chiridota heheva and its hydrothermal adaptation
文献类型：期刊论文
| 作者 | Yujin Pu1,2; Yang Zhou2; Jun Liu2; Haibin Zhang2 |
| 刊名 | GIGASCIENCE
 |
| 出版日期 | 2024-01 |
| 卷号 | 13期号:1页码:1–12 |
| 关键词 | Chiridota heheva Hi-C positively selected gene gene family unique gene |
| DOI | 10.1093/gigascience/giad107 |
| 目次 | 否 |
| 英文摘要 | Background: Chiridota heheva is a cosmopolitan holothurian well adapted to diverse deep-sea ecosystems, especially chemosynthetic
environments. Besides high hydrostatic pressure and limited light, high concentrations of metal ions also represent harsh conditions
in hydrothermal environments. Few holothurian species can live in such extreme conditions. Therefore, it is valuable to elucidate the
adaptive genetic mechanisms of C. heheva in hydrothermal environments.
Findings: Herein, we report a high-quality reference genome assembly of C. heheva from the Kairei vent, which is the first chromosome
level genome of Apodida. The chromosome-level genome size was 1.43 Gb, with a scaffold N50 of 53.24 Mb and BUSCO completeness
score of 94.5%. Contig sequences were clustered, ordered, and assembled into 19 natural chromosomes. Comparative genome analysis
found that the expanded gene families and positively selected genes of C. heheva were involved in the DNA damage repair process. The
expanded gene families and the unique genes contributed to maintaining iron homeostasis in an iron-enriched environment. The
positively selected gene RFC2 with 10 positively selected sites played an essential role in DNA repair under extreme environments.
Conclusions: This first chromosome-level genome assembly of C. heheva reveals the hydrothermal adaptation of holothurians. As
the first chromosome-level genome of order Apodida, this genome will provide the resource for investigating the evolution of class
Holothuroidea. |
| 语种 | 英语 |
| 源URL | [http://ir.idsse.ac.cn/handle/183446/11097]  |
| 专题 | 深海科学研究部_深海生物学研究室_海洋生物生态与进化研究组 研究生部 |
| 作者单位 | 1.University of Chinese Academy of Sciences, Beijing 100049, China 2.Institute of Deep-sea Science and Engineering, Chinese Academy of Sciences, Sanya 572000, China |
| 推荐引用方式 GB/T 7714 | Yujin Pu,Yang Zhou,Jun Liu,et al. A high-quality chromosomal genome assembly of the sea cucumber Chiridota heheva and its hydrothermal adaptation[J]. GIGASCIENCE,2024,13(1):1–12. |
| APA | Yujin Pu,Yang Zhou,Jun Liu,&Haibin Zhang.(2024).A high-quality chromosomal genome assembly of the sea cucumber Chiridota heheva and its hydrothermal adaptation.GIGASCIENCE,13(1),1–12. |
| MLA | Yujin Pu,et al."A high-quality chromosomal genome assembly of the sea cucumber Chiridota heheva and its hydrothermal adaptation".GIGASCIENCE 13.1(2024):1–12. |
入库方式： OAI收割
来源：深海科学与工程研究所
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