Prenatal Exposure to Legacy and Alternative Per- and Polyfluoroalkyl Substances and Neuropsychological Development Trajectories over the First 3 Years of Life
文献类型：期刊论文
| 作者 | Li, Qing-Qing6; Huang, Jinbo5; Cai, Dan4; Chou, Wei-Chun3; Zeeshan, Mohammed6; Chu, Chu2; Zhou, Yang4; Lin, Lizi6; Ma, Hui-Min1; Tang, Cuilan5 |
| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
 |
| 出版日期 | 2023 |
| 卷号 | 57期号:9页码:3746-3757 |
| 关键词 | PERFLUOROALKYL SUBSTANCES PERFLUOROOCTANE SULFONATE CHILDHOOD EXPOSURE SAS PROCEDURE PFOS ATTENTION MODELS PFASS ACIDS CORD |
| ISSN号 | 0013-936X |
| DOI | 10.1021/acs.est.2c07807 |
| 英文摘要 | The neurotoxic effects of prenatal exposure to per- and polyfluoroalkyl substances (PFAS) on offspring animals are well-documented. However, epidemiological evidence for legacy PFAS is inconclusive, and for alternative PFAS, it is little known. In this investigation, we selected 718 mother-child pairs from the Chinese Maoming Birth Cohort Study and measured 17 legacy and alternative PFAS in the third-trimester serum. Neuropsychological developments (communication, gross motor function, fine motor function, problem solving ability, and personal-social skills) were assessed at 3, 6, 12, 18, 24, and 36 months using the Ages and Stages Questionnaires 3rd edition. Trajectories of each subscale were classified into persistently low and persistently high groups via group-based trajectory modeling. Logistic regression and grouped weighted quantile sum were fitted to assess the potential effects of individual PFAS and their mixtures, respectively. Higher linear PFHxS levels were associated with elevated odds for the persistently low trajectories of communication (OR = 1.73; 95% CI: 1.12, 2.66) and problem solving ability (OR = 2.11; 95% CI: 1.14, 3.90). Similar findings were observed for linear PFOS, 1m-PFOS, PFDA, PFDoDA, PFUnDA, and legacy PFAS mixture. However, no association was observed for alternative PFAS and their mixture. We provided insights into the longitudinal links between prenatal legacy/alternative PFAS exposure and neuropsychological development trajectories over the first 3 years of life. ? 2023 American Chemical Society. |
| WOS研究方向 | Engineering, Environmental ; Environmental Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000934173800001 |
| 源URL | [http://ir.gig.ac.cn/handle/344008/80220]  |
| 专题 | 有机地球化学国家重点实验室 |
| 作者单位 | 1.State Key Laboratory of Organic Geochemistry and Guangdong Key Laboratory of Environmental Protection and Resources Utilization, Guangzhou Institute of Geochemistry, Chinese Academy of Sciences, Guangzhou; 510630, China 2.Guangdong Cardiovascular Institute, Department of Reproductive Medicine, Department of Obstetrics and Gynecology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou; 510080, China 3.Center for Environmental and Human Toxicology, Department of Environmental and Global Health, College of Public Health and Health Professions, University of Florida, Gainesville; FL; 32611, United States 4.State Environmental Protection Key Laboratory of Environmental Pollution Health Risk Assessment, South China Institute of Environmental Sciences, Ministry of Environmental Protection, Guangzhou; 510655, China 5.Maoming Maternal and Child Health Hospital, Guangdong, Maoming; 525000, China 6.Department of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou; 510080, China |
| 推荐引用方式 GB/T 7714 | Li, Qing-Qing,Huang, Jinbo,Cai, Dan,et al. Prenatal Exposure to Legacy and Alternative Per- and Polyfluoroalkyl Substances and Neuropsychological Development Trajectories over the First 3 Years of Life[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2023,57(9):3746-3757. |
| APA | Li, Qing-Qing.,Huang, Jinbo.,Cai, Dan.,Chou, Wei-Chun.,Zeeshan, Mohammed.,...&Zeng, Xiao-Wen.(2023).Prenatal Exposure to Legacy and Alternative Per- and Polyfluoroalkyl Substances and Neuropsychological Development Trajectories over the First 3 Years of Life.ENVIRONMENTAL SCIENCE & TECHNOLOGY,57(9),3746-3757. |
| MLA | Li, Qing-Qing,et al."Prenatal Exposure to Legacy and Alternative Per- and Polyfluoroalkyl Substances and Neuropsychological Development Trajectories over the First 3 Years of Life".ENVIRONMENTAL SCIENCE & TECHNOLOGY 57.9(2023):3746-3757. |
入库方式： OAI收割
来源：广州地球化学研究所
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