Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine
文献类型：期刊论文
| 作者 | Ling, Jiawei; Chan, Ben Chung-Lap; Tsang, Miranda Sin-Man; Gao, Xun; Leung, Ping Chung; Lam, Christopher Wai-Kei; Hu, Jiang-Miao ; Wong, Chun Kwok
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| 刊名 | FRONTIERS IN MEDICINE
 |
| 出版日期 | 2022 |
| 卷号 | 8页码:815075 |
| 关键词 | inflammation signaling pathways immunomodulatory therapy traditional Chinese medicine dry eye disease CHRONIC INFLAMMATORY LESIONS MEIBOMIAN GLAND DYSFUNCTION OCULAR-SURFACE OPHTHALMIC SOLUTION TEAR FILM SJOGRENS-SYNDROME ORAL DOXYCYCLINE MATRIX METALLOPROTEINASES TOPICAL CORTICOSTEROIDS CATARACT-SURGERY |
| DOI | 10.3389/fmed.2021.815075 |
| 英文摘要 | Dry eye is currently one of the most common ocular surface disease. It can lead to ocular discomfort and even cause visual impairment, which greatly affects the work and quality of life of patients. With the increasing incidence of dry eye disease (DED) in recent years, the disease is receiving more and more attention, and has become one of the hot research fields in ophthalmology research. Recently, with the in-depth research on the etiology, pathogenesis and treatment of DED, it has been shown that defects in immune regulation is one of the main pathological mechanisms of DED. Since the non-specific and specific immune response of the ocular surface are jointly regulated, a variety of immune cells and inflammatory factors are involved in the development of DED. The conventional treatment of DED is the application of artificial tears for lubricating the ocular surface. However, for moderate-to-severe DED, treatment with anti-inflammatory drugs is necessary. In this review, the immunomodulatory mechanisms of DED and the latest research progress of its related treatments including Chinese medicine will be discussed. |
| WOS记录号 | WOS:000749877100001 |
| 源URL | [http://ir.kib.ac.cn/handle/151853/75649]  |
| 专题 | 中国科学院昆明植物研究所 |
| 推荐引用方式 GB/T 7714 | Ling, Jiawei,Chan, Ben Chung-Lap,Tsang, Miranda Sin-Man,et al. Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine[J]. FRONTIERS IN MEDICINE,2022,8:815075. |
| APA | Ling, Jiawei.,Chan, Ben Chung-Lap.,Tsang, Miranda Sin-Man.,Gao, Xun.,Leung, Ping Chung.,...&Wong, Chun Kwok.(2022).Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine.FRONTIERS IN MEDICINE,8,815075. |
| MLA | Ling, Jiawei,et al."Current Advances in Mechanisms and Treatment of Dry Eye Disease: Toward Anti-inflammatory and Immunomodulatory Therapy and Traditional Chinese Medicine".FRONTIERS IN MEDICINE 8(2022):815075. |
入库方式： OAI收割
来源：昆明植物研究所
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