State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants
文献类型:期刊论文
作者 | Jing, Qi3,4; Wang, Hongda3,4; Li, Xue3,4; Cui, Dianxin3,4; Zhao, Yuying3,4; Wang, Wei3,4; Hu, Ying4; Jiang, Meiting3,4; Gao, Xiumei2,3,4; Guo, Dean1,3,4![]() |
刊名 | TRAC-TRENDS IN ANALYTICAL CHEMISTRY
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出版日期 | 2024-10-01 |
卷号 | 179页码:25 |
关键词 | Mass spectrometry imaging Medicinal and edible plant Mapping knowledge Ionization technology Spatial distribution Spatial metabolomics |
ISSN号 | 0165-9936 |
DOI | 10.1016/j.trac.2024.117878 |
通讯作者 | Guo, Dean(daguo@simm.ac.cn) ; Yang, Wenzhi(wzyang0504@tjutcm.edu.cn) |
英文摘要 | Modern researches on medicines and foods have proposed greatly increasing demand on the spatial distribution analysis of the medicinal and edible plants (MEPs). Mass spectrometry imaging (MSI) is a newly flourishing imaging method widely employed in the spatial distribution analysis of various tissue samples. Relying on versatile ionization techniques and improvement in sample processing, MSI can more quickly and completely characterize the metabolites in MEPs. This review gave a comprehensive summary on the principles, characteristics, general workflows, and typical applications of MSI on MEPs in the past decade (2013-2023). Localization analysis of the multi-category compounds by MSI could facilitate characterization of the medicinal/toxic/ nutritional parts of MEPs, the phytochemical changes during the growth or processing, spatial metabolomics differentiation among the species, in vivo animal tissue distribution of the active components, and spatial metabolomics for drug discovery and target elucidation, beneficial to pharmacological mechanism elucidation, quality control, cultivation, and breeding of MEPs. |
WOS关键词 | ABLATION ELECTROSPRAY-IONIZATION ; MOLECULAR-WEIGHT COMPOUNDS ; SPATIAL-DISTRIBUTION ; ATMOSPHERIC-PRESSURE ; SAMPLE PREPARATION ; TISSUE-SECTIONS ; PANAX-GINSENG ; MOUSE KIDNEY ; R PACKAGE ; LTP-MSI |
资助项目 | Science & Technology Program of Haihe Laboratory of Modern Chinese Medicine[22HHZYSS00012] ; National Natural Science Foundation of China[82374030] ; Tianjin Outstanding Youth Fund[23JCJQJC00030] ; Foundation of State Key Laboratory of Component-based Chinese Medicine[CBQM2022103] ; Foundation of State Key Laboratory of Component-based Chinese Medicine[CBCM2023202] ; Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine[ZYYCXTD-C-202009] |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:001279469500001 |
出版者 | ELSEVIER SCI LTD |
源URL | [http://119.78.100.183/handle/2S10ELR8/312553] ![]() |
专题 | 中国科学院上海药物研究所 |
通讯作者 | Guo, Dean; Yang, Wenzhi |
作者单位 | 1.Chinese Acad Sci, Shanghai Res Ctr Modernizat Tradit Chinese Med, Natl Engn Lab TCM Standardizat Technol, Shanghai Inst Mat Med, 501 Haike Rd, Shanghai 201203, Peoples R China 2.Tianjin Univ Tradit Chinese Med, Key Lab Pharmacol Tradit Chinese Med Formulae, Minist Educ, 10 Poyanghu Rd, Tianjin 301617, Peoples R China 3.Haihe Lab Modern Chinese Med, 10 Poyanghu Rd, Tianjin 301617, Peoples R China 4.Tianjin Univ Tradit Chinese Med, State Key Lab Chinese Med Modernizat, 10 Poyanghu Rd, Tianjin 301617, Peoples R China |
推荐引用方式 GB/T 7714 | Jing, Qi,Wang, Hongda,Li, Xue,et al. State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2024,179:25. |
APA | Jing, Qi.,Wang, Hongda.,Li, Xue.,Cui, Dianxin.,Zhao, Yuying.,...&Yang, Wenzhi.(2024).State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,179,25. |
MLA | Jing, Qi,et al."State-of-the-art application of mass spectrometry imaging covering the medicinal and edible plants".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 179(2024):25. |
入库方式: OAI收割
来源:上海药物研究所
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