A Miniaturized and Highly Sensitive "Windmill" Three-Channel Fluorescence Detector for Simultaneous Detection of Various Mycotoxins
文献类型：期刊论文
| 作者 | Wang, Chuanliang3,4; Sha, Tao2,4; Lu, Jiashan4; Guan, Yafeng1,4; Geng, Xuhui4 |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2024-06-14 |
| 卷号 | 96期号:25页码:10121-10126 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/acs.analchem.4c00311 |
| 英文摘要 | A novel "windmill" three-channel light-emitting diode induced fluorescence detector (LED-IF) was proposed to maximize the excitation efficiency and fluorescence collection efficiency. Compared with the typical collinear arrangement, the fluorescence intensity of the three channels was increased by 7.85, 3.88, and 2.94 times, respectively. The compact shaping optical path was designed to obtain higher excitation efficiency and a lower background stray light effect caused by high divergence angle high-power ultraviolet (UV)-LEDs simultaneously, which increased the sensitivity of three channels by 4.6 to 5.7 times. It was found that using a photodiode (PD) with a flat window and a larger photosensitive surface can collect the Lambertian emission fluorescence in the flow cell more efficiently, increasing the signal-to-noise ratio of each channel 1.3 to 1.8 times. The limits of detection (LODs, 3 times peak-peak noise) of aflatoxin B-2 (AFB(2)), ochratoxin (OTA), and zearalenone (ZEN) were 0.33, 1.80, and 28.2 ng/L, respectively. Finally, six mycotoxins were analyzed simultaneously by the detector coupling with HPLC. The results showed that the sensitivity of the detector was at the best level to date, which was better than that of the top commercial fluorescence detectors (FLDs). The developed detector has the advantages of having small volume, low cost, and long lifetime and being robust, which has wide application and market prospects. |
| 资助项目 | National Natural Science Foundation of China[22074146] ; General Program of the National Natural Science Foundation of China[YJKYYQ20210038] ; Instrument Developing Project of the Chinese Academy of Sciences[2022RJ02] ; Dalian Science and Technology Talent Innovation Support Plan |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001248671200001 |
| 出版者 | AMER CHEMICAL SOC |
| 资助机构 | National Natural Science Foundation of China ; General Program of the National Natural Science Foundation of China ; Instrument Developing Project of the Chinese Academy of Sciences ; Dalian Science and Technology Talent Innovation Support Plan |
| 源URL | [http://ir.idsse.ac.cn/handle/183446/11545]  |
| 专题 | 深海科学研究部 |
| 通讯作者 | Geng, Xuhui |
| 作者单位 | 1.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Sanya 572000, Peoples R China 2.South Cent Minzu Univ, Wuhan 430074, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Key Lab Deep Sea Composit Detect Technol Liaoning, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Chuanliang,Sha, Tao,Lu, Jiashan,et al. A Miniaturized and Highly Sensitive "Windmill" Three-Channel Fluorescence Detector for Simultaneous Detection of Various Mycotoxins[J]. ANALYTICAL CHEMISTRY,2024,96(25):10121-10126. |
| APA | Wang, Chuanliang,Sha, Tao,Lu, Jiashan,Guan, Yafeng,&Geng, Xuhui.(2024).A Miniaturized and Highly Sensitive "Windmill" Three-Channel Fluorescence Detector for Simultaneous Detection of Various Mycotoxins.ANALYTICAL CHEMISTRY,96(25),10121-10126. |
| MLA | Wang, Chuanliang,et al."A Miniaturized and Highly Sensitive "Windmill" Three-Channel Fluorescence Detector for Simultaneous Detection of Various Mycotoxins".ANALYTICAL CHEMISTRY 96.25(2024):10121-10126. |
入库方式： OAI收割
来源：深海科学与工程研究所
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