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  4. 深海科学研究部
  5. 深海生物学研究室
  6. 海洋哺乳动物与海洋生物声学研究组
Sirenian genomes illuminate the evolution of fully aquatic species within the mammalian superorder afrotheria

文献类型：期刊论文

作者Tian, Ran12; Zhang, Yaolei9,10,11; Kang, Hui6,7,8; Zhang, Fan12; Jin, Zhihong12; Wang, Jiahao10,11; Zhang, Peijun8; Zhou, Xuming4,5; Lanyon, Janet M.3; Sneath, Helen L.3
刊名NATURE COMMUNICATIONS
出版日期2024-07-02
卷号15期号:1页码:19
DOI10.1038/s41467-024-49769-x
英文摘要Sirenians of the superorder Afrotheria were the first mammals to transition from land to water and are the only herbivorous marine mammals. Here, we generated a chromosome-level dugong (Dugong dugon) genome. A comparison of our assembly with other afrotherian genomes reveals possible molecular adaptations to aquatic life by sirenians, including a shift in daily activity patterns (circadian clock) and tolerance to a high-iodine plant diet mediated through changes in the iodide transporter NIS (SLC5A5) and its co-transporters. Functional in vitro assays confirm that sirenian amino acid substitutions alter the properties of the circadian clock protein PER2 and NIS. Sirenians show evidence of convergent regression of integumentary system (skin and its appendages) genes with cetaceans. Our analysis also uncovers gene losses that may be maladaptive in a modern environment, including a candidate gene (KCNK18) for sirenian cold stress syndrome likely lost during their evolutionary shift in daily activity patterns. Genomes from nine Australian locations and the functionally extinct Okinawan population confirm and date a genetic break similar to 10.7 thousand years ago on the Australian east coast and provide evidence of an associated ecotype, and highlight the need for whole-genome resequencing data from dugong populations worldwide for conservation and genetic management.
WOS关键词DUGONG DUGONG-DUGON ; PHYLOGENY-AWARE ALIGNMENT ; POSITIVE SELECTION ; POPULATION HISTORY ; THERMAL-CONDUCTIVITY ; INSULATIVE CAPACITY ; READ ALIGNMENT ; GENE ; GENERATION ; AUSTRALIA
资助项目Chinese Ministry of Science and Technology National Key Programme of Research and Development[2022YFF1301601] ; National Natural Science Foundation of China[42225604] ; National Natural Science Foundation of China[32270441] ; Young Elite Scientists Sponsorship Program of the China Association for Science and Technology[2023QNRC001] ; Sea World Foundation (Australia) ; Winifred Violet Scott Foundation ; One Belt and One Road Science and Technology Co-operation Special Program of the International Partnership Program of the Chinese Academy of Sciences[183446KYSB20200016] ; Specially-appointed Professor Program of Jiangsu Province ; Jiangsu Foreign Expert Bureau ; Jiangsu Provincial Department of Technology[JSSCTD202142]
WOS研究方向Science & Technology - Other Topics
语种英语
WOS记录号WOS:001261751100014
出版者NATURE PORTFOLIO
资助机构Chinese Ministry of Science and Technology National Key Programme of Research and Development ; National Natural Science Foundation of China ; Young Elite Scientists Sponsorship Program of the China Association for Science and Technology ; Sea World Foundation (Australia) ; Winifred Violet Scott Foundation ; One Belt and One Road Science and Technology Co-operation Special Program of the International Partnership Program of the Chinese Academy of Sciences ; Specially-appointed Professor Program of Jiangsu Province ; Jiangsu Foreign Expert Bureau ; Jiangsu Provincial Department of Technology
源URL[http://ir.idsse.ac.cn/handle/183446/11509]  
专题深海科学研究部_深海生物学研究室_海洋哺乳动物与海洋生物声学研究组
通讯作者Fan, Guangyi; Li, Songhai; Seim, Inge
作者单位1.BGI Res, State Key Lab Agr Genom, Shenzhen 518083, Peoples R China
2.Univ Adelaide, Sch Vet Sci, Roseworthy 5371, Australia
3.Univ Queensland, Sch Environm, St Lucia 4072, Australia
4.Univ Sci & Technol China, Sch Life Sci, Hefei 230027, Peoples R China
5.Chinese Acad Sci, Key Lab Anim Ecol & Conservat Biol, Inst Zool, Beijing 100101, Peoples R China
6.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China
7.Chinese Acad Sci, Innovat Res Ctr Aquat Mammals, Wuhan 430072, Peoples R China
8.Chinese Acad Sci, Inst Deep Sea Sci & Engn, Marine Mammal & Marine Bioacoust Lab, Sanya 572000, Peoples R China
9.Qingdao Key Lab Marine Genom BGI Res, Qingdao 266555, Peoples R China
10.BGI Res, Shenzhen 518083, Peoples R China
推荐引用方式
GB/T 7714		 Tian, Ran,Zhang, Yaolei,Kang, Hui,et al. Sirenian genomes illuminate the evolution of fully aquatic species within the mammalian superorder afrotheria[J]. NATURE COMMUNICATIONS,2024,15(1):19.
APA Tian, Ran.,Zhang, Yaolei.,Kang, Hui.,Zhang, Fan.,Jin, Zhihong.,...&Seim, Inge.(2024).Sirenian genomes illuminate the evolution of fully aquatic species within the mammalian superorder afrotheria.NATURE COMMUNICATIONS,15(1),19.
MLA Tian, Ran,et al."Sirenian genomes illuminate the evolution of fully aquatic species within the mammalian superorder afrotheria".NATURE COMMUNICATIONS 15.1(2024):19.

入库方式： OAI收割

来源：深海科学与工程研究所

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