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Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin

文献类型：期刊论文

作者Xiang, Jiawen4,5; Qi, Ji3,4; Hu, Die1,4; Wang, Chao4,6; Wang, Liyan4; Wu, Yixuan4; Chen, Jiadong3; Zhang, Zhiyang4,5; Wang, Xiaoyan2; Li, Bowei4,5
刊名JOURNAL OF HAZARDOUS MATERIALS
出版日期2024-05-05
卷号469页码:10
关键词Gonyautoxin 1/4 Colorimetric sensor Microfluidic device Molecularly imprinted polymer
ISSN号0304-3894
DOI10.1016/j.jhazmat.2024.133969
通讯作者Li, Bowei(bwli@yic.ac.cn) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要Marine algal toxin contamination is a major threat to human health. Thus, it is crucial to develop rapid and onsite techniques for detecting algal toxins. In this work, we developed colorimetric cloth and paper hybrid microfluidic devices (mu CPADs) for rapid detection of gonyautoxin (GTX1/4) combined with molecularly imprinted polymers. In addition, the metal -organic frameworks (MOFs) composites were applied for this approach by their unique features. Guanosine serves as a dummy template for surface imprinting and has certain structural advantages in recognizing gonyautoxin. MOF@MIPs composites were able to perform a catalytic color reaction using hydrogen peroxide-tetramethylbenzidine for the detection of GTX1/4. The cloth -based sensing substrates were assembled on origami mu PADs to form user-friendly, miniaturized colorimetric mu CPADs. Combined with a smartphone, the proposed colorimetric mu CPADs successfully achieved a low limit of detection of 0.65 mu g/L within the range of 1-200 mu g/L for rapid visual detection of GTX1/4. Moreover, the GTX1/4 of real shellfish and seawater samples were satisfactorily detected to indicate the application prospect of the mu CPADs. The proposed method shows good potential in the low-cost, stable establishment of assays for the rapid detection of environmental biotoxins.
WOS关键词PERFORMANCE LIQUID-CHROMATOGRAPHY ; APTAMER ; DESIGN ; TOXINS ; SENSOR
WOS研究方向Engineering ; Environmental Sciences & Ecology
语种英语
WOS记录号WOS:001202721600001
资助机构National Natural Science Foundation of China Major Scientific Research Instrument Development Project ; National Natural Science Foundation of China ; Shandong Provincial Natural Science Foundation Key Project of China ; Open Fund Project of Key Laboratory of Ocean Observation Technology
源URL[http://ir.yic.ac.cn/handle/133337/36110]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者Li, Bowei; Chen, Lingxin
作者单位1.Yantai Univ, Sch Chem & Chem Engn, Yantai 264005, Peoples R China
2.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
3.Chung Ang Univ, Dept Chem, Seoul 06974, South Korea
4.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
6.Harbin Inst Technol Weihai, Dept Appl Chem, Weihai 264209, Peoples R China
推荐引用方式
GB/T 7714		 Xiang, Jiawen,Qi, Ji,Hu, Die,et al. Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin[J]. JOURNAL OF HAZARDOUS MATERIALS,2024,469:10.
APA Xiang, Jiawen.,Qi, Ji.,Hu, Die.,Wang, Chao.,Wang, Liyan.,...&Chen, Lingxin.(2024).Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin.JOURNAL OF HAZARDOUS MATERIALS,469,10.
MLA Xiang, Jiawen,et al."Molecularly imprinted metal-organic frameworks assisted cloth and paper hybrid microfluidic devices for visual detection of gonyautoxin".JOURNAL OF HAZARDOUS MATERIALS 469(2024):10.

入库方式： OAI收割

来源：烟台海岸带研究所

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