Ratiometric fluorescent and electrochemiluminescent dual modal assay for detection of 2,6-pyridinedicarboxylic acid as an anthrax biomarker
文献类型：期刊论文
| 作者 | Xu, Ning1; Li, Xin1; Luan, Feng1; Tian, Chunyuan1; Zhang, Zhiyang2 ; Chen, Lingxin2; Zhuang, Xuming1
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| 刊名 | ANALYTICA CHIMICA ACTA
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| 出版日期 | 2024-02-01 |
| 卷号 | 1288页码:9 |
| 关键词 | 6-Pyridinedicarboxylic acid Ratiometric fluorescent probe Electrochemiluminescence Metal -organic framework Bacillus anthracis |
| ISSN号 | 0003-2670 |
| DOI | 10.1016/j.aca.2023.342181 |
| 通讯作者 | Chen, Lingxin(lxchen@yic.ac.cn) ; Zhuang, Xuming(xmzhuang@iccas.ac.cn) |
| 英文摘要 | 2,6-pyridinedicarboxylic acid (DPA) is an excellent biomarker of Bacillus anthracis (B. anthracis). The sensitive detection of DPA, especially through visual point -of -care testing, was significant for accurate and rapid diagnosis of anthrax to timely prevent anthrax disease or biological terrorist attack. Herein, a ratiometric fluorescent (RFL) and electrochemiluminescent (ECL) dual -mode detection platform with a lanthanide ion -based metal -organic framework (Ln-MOF, i.e., M/Y-X: M = Eu, Y = Tb, and X = 4,4 ',4 ''-s-triazine-1,3,5-triyltri-m-aminobenzoic acid) was developed. Eu/Tb-TATAB nanoparticles were constructed to identify DPA. The R -FL detection platform quantitatively detected DPA by monitoring the I545/I617 ratio of the characteristic fluorescence peak intensities of Tb3+ ions and Eu3+ ions. The ECL sensing platform successfully quantified DPA by exploiting the burst effect of DPA on the ECL signal. The above methods had highly sensitive and rapid detection of DPA in water and serum samples. The results showed that this dual -mode detection platform may be projected to be a powerful instrument for preventing related biological warfare and bio-terrorism. |
| WOS关键词 | BACTERIAL SPORE DETECTION ; BACILLUS-ANTHRACIS ; DIPICOLINIC ACID ; PROBE ; MICRORNA |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001156258600001 |
| 资助机构 | Natural Sci- ence Foundation of Shandong Province |
| 源URL | [http://ir.yic.ac.cn/handle/133337/36346]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 烟台海岸带研究所_近岸生态与环境实验室 |
| 通讯作者 | Chen, Lingxin; Zhuang, Xuming |
| 作者单位 | 1.Yantai Univ, Coll Chem & Chem Engn, Yantai 264005, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Shandong Key Lab Coastal Environm Proc, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Ning,Li, Xin,Luan, Feng,et al. Ratiometric fluorescent and electrochemiluminescent dual modal assay for detection of 2,6-pyridinedicarboxylic acid as an anthrax biomarker[J]. ANALYTICA CHIMICA ACTA,2024,1288:9. |
| APA | Xu, Ning.,Li, Xin.,Luan, Feng.,Tian, Chunyuan.,Zhang, Zhiyang.,...&Zhuang, Xuming.(2024).Ratiometric fluorescent and electrochemiluminescent dual modal assay for detection of 2,6-pyridinedicarboxylic acid as an anthrax biomarker.ANALYTICA CHIMICA ACTA,1288,9. |
| MLA | Xu, Ning,et al."Ratiometric fluorescent and electrochemiluminescent dual modal assay for detection of 2,6-pyridinedicarboxylic acid as an anthrax biomarker".ANALYTICA CHIMICA ACTA 1288(2024):9. |
入库方式： OAI收割
来源：烟台海岸带研究所
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