Synthesis and characterization of novel carboxymethyl inulin derivatives bearing cationic Schiff bases with antioxidant potential
文献类型：期刊论文
| 作者 | Chen, Yuan3; Zhang, Hongwu3; Chen, Qiuhong1; Mi, Yingqi1,2; Guo, Zhanyong1
|
| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
 |
| 出版日期 | 2024-08-01 |
| 卷号 | 275页码:11 |
| 关键词 | Carboxymethyl inulin Schiff base Antioxidant activity Cytotoxicity |
| ISSN号 | 0141-8130 |
| DOI | 10.1016/j.ijbiomac.2024.133761 |
| 通讯作者 | Mi, Yingqi(yqmi@yic.ac.cn) ; Guo, Zhanyong(zhanyongguo@hotmail.com) |
| 英文摘要 | This study aimed to enhance the antioxidant activity of carboxymethyl inulin (CMI) by chemical modification. Therefore, a series of cationic Schiff bases bearing heteroatoms were synthesized and incorporated into CMI via ion exchange reactions, ultimately preparing 10 novel CMI derivatives (CMID). Their structures were confirmed by Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) spectroscopy. The radical scavenging activities and reducing power of inulin, CMI, and CMID were studied. The results revealed a significant enhancement in antioxidant activity upon the introduction of cationic Schiff bases into CMI. Compared to commercially available antioxidant Vc, CMID demonstrated a broader range of antioxidant activities across the four antioxidant systems analyzed in this research. In particular, CMID containing quinoline (6QSCMI) exhibited the strongest hydroxyl radical scavenging activity, with a scavenging rate of 93.60 % at 1.6 mg mL- 1. The CMID bearing imidazole (2MSCMI) was able to scavenge 100 % of the DPPH radical at 1.60 mg mL- 1. Furthermore, cytotoxicity experiments showed that the products had good biocompatibility. These results are helpful for evaluating the feasibility of exploiting these products in the food, biomedical, and cosmetics industries. |
| WOS关键词 | OXIDATIVE STRESS ; COMPLEXES |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:001288611900001 |
| 资助机构 | Natural Science Foundation of Shandong Province of China ; China Post-doctoral Science Foundation |
| 源URL | [http://ir.yic.ac.cn/handle/133337/35828]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Mi, Yingqi; Guo, Zhanyong |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Ludong Univ, Coll Chem & Mat Sci, Yantai 264025, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yuan,Zhang, Hongwu,Chen, Qiuhong,et al. Synthesis and characterization of novel carboxymethyl inulin derivatives bearing cationic Schiff bases with antioxidant potential[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2024,275:11. |
| APA | Chen, Yuan,Zhang, Hongwu,Chen, Qiuhong,Mi, Yingqi,&Guo, Zhanyong.(2024).Synthesis and characterization of novel carboxymethyl inulin derivatives bearing cationic Schiff bases with antioxidant potential.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,275,11. |
| MLA | Chen, Yuan,et al."Synthesis and characterization of novel carboxymethyl inulin derivatives bearing cationic Schiff bases with antioxidant potential".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 275(2024):11. |
入库方式： OAI收割
来源：烟台海岸带研究所
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